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Latest Posters

Poster

Development and Assessment of Non-Infected and Infected Skin Models Using MALDI-MSI

Infections have detrimental effects on wound healing leading to chronic wound formation. The use of labskin,a living skin model, in combination with mass spectrometry imaging, provides a good model for assessing wound healing factors.
Poster

Analysis of the Effect of Aggregated β-Amyloid on Cellular Signaling Pathways Critical for Memory in Alzheimer’s Disease

Here we evaluate the ability to detect changes in phosphorylation levels of ERK and CREB following treatment with Aβ using the SH-SY5Y neuroblastoma cell line.
Poster

Complete alignment identification of CRISPR-Cas9 genomic off-targets using Edit-R CRISPR specificity tool and a comprehensive analysis of positional mismatch tolerance

A web tool that performs complete crRNA specificity checking is introduced. In addition, we evaluated positional off-targeting of the CRISPR system.
Poster

MicroRNAs as Bile-Based Biomarkers in Pancreatic Cancer and Biliary Tract Cancers

In this study, the role of miRNAs has been assessed in a large cohort of pancreatic cancer.
Poster

Point of Care Ultrasound in Risk Stratification of Acute Pulmonary Embolism

We present a case of pulmonary embolism in a young man who
benefitted from point of care ultrasound. His management was
changed significantly with the results despite initial risk stratification
suggesting ambulatory management.
Poster

Is Oxford Nanopore Technology Ready for Clinical Diagnostics?

Our objective is to validate diagnostic services using Oxford Nanopore’s Minion in the first instance and to evaluate the cost and performance compared to existing sequencing technology in areas such as tumour DNA sequencing (and circulating tumour DNA), virology, microbiology, genetics and HLA-typing.
Poster

MHV68 Infection in a Novel rag2 F62L/F62L Mouse Model Based on a Patient with CID-G/AI Phenotype

MHV-68 infection in our rag2 mouse model induced increased antibody responses to virus and self and inflammatory disease in end organs. Major mechanism of inflammatory infiltrates and autoantibody generation is yet to be determined
Poster

Rare Diagnosis of Malignant Mesothelioma in a Young Patient with Rheumatoid Arthritis

This is a rare presentation of malignant pleural mesothelioma in a young female patient with rheumatoid arthritis and no known asbestos exposure.
Poster

Onchocerca Diagnostic Testing of Polymorphisms; Effects of Antigenic Mutations on Detection of Antibodies by OV-16 ELISA

Here, we have identified the particular polymorphism responsible for the loss of monoclonal antibody reactivity and investigated the potential effect these polymorphisms may have on the sensitivity of the Ov16 ELISA for the detection of parasite exposure.
Poster

Acoustic Startle Response as a Prognostic Tool for Traumatic Brain Injury

The Acoustic Startle Reflex (ASR) is a brain-stem mediated, tri-synaptic response to acoustic stimuli involving involuntary contraction of major muscle groups. Previous studies have demonstrated that this response is suppressed following the fluid-percussion model of traumatic brain injury (TBI). The possibility exists that the suppression of this response could be exploited for prognostic purposes.
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