Molecular Abnormalities in Schizophrenia: Neurotransmission, Oxidative Stress, and Apoptosis

Schizophrenia affects 1% of the world’s population.
• Broad, heterogeneous range of symptoms hinders the effectiveness of current therapies.
• New models reproducing core schizophrenia features are needed to elucidate pathological disease mechanisms, identify biomarkers for improved diagnosis and discover potential novel drug targets.
• A multi-platform approach was employed to analyse distinct brain regions implicated in schizophrenia.