Point-of-Care Diagnostics for Sexually Transmitted Infections
Poster Aug 25, 2011
Pascal Craw, Wamadeva Balachandran
This poster introduces the recently enlarged DoCLab research group at Brunel University, London. This large multidisciplinary group brings together electronic, mechanical and computer engineers with molecular biologists, biochemists and clinical collaborators to develop fully integrated, multiplex Point-Of-Care-Tests (POCT) for the self- diagnosis of infectious diseases.
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Our results indicate that MS modifications are required for experiments with co-electroporation of Cas9 mRNA and synthetic gRNA, yet have no impact on editing efficiency when delivered with lipid-based transfection reagents.READ MORE
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The recent fast advancement of next generation sequencing (NGS) technologies allowing for unprecedented speed and accuracy in analyzing viral genomes are opening new ways to further improve diagnostic genotyping of HCV.
A Novel Cell-Free DNA Extraction System for Cancer DiagnosticsPoster
We developed a magnetic bead-based cfDNA extraction kit and integrated it into the automated qPCR- and NGS-based IVD workflows. In this study we are compering this magnetic beads-based cfDNA extraction system with a column-based method.READ MORE