We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Exosomics Siena Launches Exosome-Based Liquid Biopsy Solutions for the Selective Analysis of Tumor-Derived DNA and RNA
Product News

Exosomics Siena Launches Exosome-Based Liquid Biopsy Solutions for the Selective Analysis of Tumor-Derived DNA and RNA

Exosomics Siena Launches Exosome-Based Liquid Biopsy Solutions for the Selective Analysis of Tumor-Derived DNA and RNA
Product News

Exosomics Siena Launches Exosome-Based Liquid Biopsy Solutions for the Selective Analysis of Tumor-Derived DNA and RNA


Want a FREE PDF version of This Product News?

Complete the form below and we will email you a PDF version of "Exosomics Siena Launches Exosome-Based Liquid Biopsy Solutions for the Selective Analysis of Tumor-Derived DNA and RNA"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

Exosomics Siena S.p.A., a pioneer and world leader in exosome-based diagnostics, announced the launch of its first proprietary liquid biopsy solutions, SeleCTEV™ DNA and SortEV™ RNA, for the selective isolation of tumor-derived nucleic acids from complex biofluids such as plasma or serum.

Distinct from current liquid biopsy methods, where total nucleic acids are harvested from blood with low amounts of tumor-derived genetic material, Exosomics Siena’s technologies can provide pre-analytical kits based on enriched tumor-derived exosomes and therefore enriched tumor-derived genetic material.

Exosomes are small extracellular vesicles present in all human biofluids and contain DNA, RNA and proteins originating from their parent cells. Enriching tumor exosomes, based on relevant pan-tumor markers, offers a more specific and sensitive diagnostic approach when compared with traditional liquid biopsy methods.

SeleCTEV™-DNA and SortEV™-RNA kits are novel and simple solutions that exploit Exosomics Siena’s proprietary technology to purify tumor-derived exosomes. Each technology uses a unique affinity method to select tumor-derived exosomes from which the DNA or RNA, respectively, can be extracted. Additionally, the SeleCTEV™-DNA kit can be used to isolate circulating tumor-derived, cell-free DNA in addition to exosome-shuttled DNA. At this time, the kits are released for research use only.

Exosomics Siena is also working on the development and clinical validation of an early pan-cancer screening assay projected to be launched in 2021. The Cancer-rEVeal™ assay will demonstrate both the power of exosomes as a vehicle of multiple classes of biomarkers relevant for next-generation diagnostics and the unique expertise and approach of this growing company.

“Exosomics Siena is proud to announce the launch of the first products in its pipeline geared at enabling the next generation of liquid biopsy tests,” said Antonio Chiesi, MD, CEO of Exosomics Siena. “Our proprietary technology around tumor-exosome enrichment and isolation coupled with optimized nucleic acid extraction will allow analytical kit developers to create better assays to screen for, diagnose and monitor cancer patients.”

Behzad Mahdavi, PhD, MBA, Chairman of the Board for Exosomics Siena and Vice President, Strategic Innovation at Lonza, said: “As part of Lonza’s wider strategy in developing exosomes, we have chosen to invest in Exosomics Siena as we believe their approach will have advantages over other non-invasive cancer tests currently on the market or in development. Because Exosomics Siena has extensive expertise in harnessing the power of exosomes in cancer diagnostics, Lonza is supporting this innovative company as they develop a platform that will greatly benefit patients."
Advertisement