We've updated our Privacy Policy to make it clearer how we use your personal data. We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement

Hamamatsu Introduces the ORCA-Flash4.0 sCMOS Camera

Listen with
Speechify
0:00
Register for free to listen to this article
Thank you. Listen to this article using the player above.

Want to listen to this article for FREE?

Complete the form below to unlock access to ALL audio articles.

Read time: Less than a minute

Hamamatsu Photonics has introduced the new ORCA-Flash4.0 sCMOS camera. In recent years, trying to detect low level or fast fluorescence signals has proved challenging and an EM-CCD camera was commonly used, however, with the arrival of the ORCA-Flash4.0 that situation has now changed.

The ORCA-Flash4.0 is the first camera to be able to deliver better signal-to-noise than EM-CCDs, cooled CCDs and first-generation sCMOS cameras for low-level, fast, fluorescence imaging. The ORCA-Flash4.0’s high sensitivity means extreme versatility.

This unique camera covers a wide range of imaging needs, including super resolution microscopy, TIRF microscopy, live cell GFP, high-speed calcium ion imaging, FRET, real-time confocal microscopy and many more.

The ORCA-Flash4.0 has quantum efficiency values of over 70% at 600 nm and 50% at 750 nm and has only 1.3 electrons of read noise (at 100 full-resolution frames per second) with continuous high speed acquisition at full resolution.

This unique combination of high quantum efficiency and low noise, in the absence of EM-CCD multiplicative noise, means that researchers are already pushing back the boundaries of what has been possible to image until now.

With a 4.0 megapixel sCMOS sensor (6.5 μm pixel size), the ORCA-Flash4.0 is ideally suited for demanding microscopy applications.

Conventional wisdom has always dictated that customers had to sacrifice sensitivity or speed or resolution - the new ORCA-Flash4.0 gives imaging without compromise.