Sera-Mag™ Streptavidin-Coated Magnetic Beads and SpeedBeads

Sera-Mag™ Streptavidin-Coated Magnetic Beads and SpeedBeads exhibit high affinity and sensitivity for biotinylated target molecules, along with fast reaction kinetics, increasing throughput and precision for genomic and proteomic applications.

- Available with low (2500 to 3500 pmol/mg), medium (3500 to 4500 pmol/mg) or high (4500 to 5500 pmol/mg) nominal biotin binding capacities to optimize assay development
- Low dissociation constant ensures tight ligand binding
- Low non-specific binding for greater precision and accuracy
- Combines large surface area, high sensitivity, physical stability, and fast reaction kinetics
- Even streptavidin coating for reliable results

Find out which magnetic bead chemistry meets your application requirements in Magbeads 101: A guide to choosing and using magnetic beads and explore ways to optimize your magnetic bead workflow in Scientists guide to magnetic beads

The uniform, nominal 1 μm diameter provides high surface area and excellent lot-to-lot reproducibility.
Sera-Mag™ SpeedBeads and Sera-Mag™ Streptavidin-Coated Magnetic Particles combine fast reaction kinetics and low non-specific binding for increased throughput and precision in immunoassay and molecular biology applications such as sample preparation and assay development for genomics and proteomics.

Streptavidin Coating Targets Biotinylated Molecules

Compounds that are difficult to attach to particle surfaces by conventional means may be amenable to biotinylation. Sera-Mag™ SpeedBeads and Sera-Mag™ Streptavidin-Coated Magnetic Particles provide a high biotin-binding capacity along with a strong affinity for targeted, biotin-labeled molecules.

High performance magnetic particles for protein purification and sample prep

The entire range of Sera-Mag™ encapsulated magnetic particles are characterized by high binding capacity, excellent stability, low nonspecific binding, high sensitivity, very slow settling rates, and fast reaction kinetics.

Sera-Mag™ and SpeedBead technology

The core of each particle is made by a free radical emulsion polymerization of styrene and acid monomer. One (Sera-Mag™) or two (Sera-Mag™ SpeedBeads) layers of magnetite are then coated onto this core, while the surface is modified to minimize non-specific binding of proteins. Due to the extra magnetite layer, SpeedBeads respond twice as fast to a magnetic field as the original Sera-Mag™ particles.

Customized for your workflows

Magnetic particles may need further processing before they are ready to use for your particular application. Therefore, we can provide personalized magnetic bead solutions that fit seamlessly into your workflows, often saving you time and money in the process. We aim to provide product that is ready to use with little or no need for further modification. This allows you to focus on the science that matters. To learn more, please visit our custom manufacturing services page.

Have you considered your magnetic separation rack?

Cytiva’s Magnetic Separation Rack 15 mL is a 3D printed, magnetized tube rack with a strong, removable magnetic force and easy pipette access. It facilitates high capture, retention, and release of magnetic beads from various liquid sample media, allowing high-throughput, parallel processing of up to six 15 mL samples.

Find out more about magnetic separation racks

Our ISO 13485 accredited manufacturing center of excellence adheres to the standards in the manufacturing process, ensuring the highest quality and compliance with international medical device regulations.