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Tfh Cells and Associated Cytokines: The B Cell Modulators

Tfh Cells and Associated Cytokines: The B Cell Modulators


The T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells essential for the survival, affinity maturation, and class switch recombination of B cells. They promote effective B-cell antibody-mediated immune responses. Dysregulation of Tfh cells is linked to autoimmune disorder systemic sclerosis and chronic graft-versus-host-disease. These cells also play essential roles in allergies, asthma, viral infections, and cancer. There is a growing interest in utilizing these cells to improve therapeutic and vaccination strategies.

Several prominent cytokines positively or negatively regulate Tfh cell differentiation and development. Sino Biological has developed a comprehensive collection of high-quality cytokines that support the research in the development and applications of Tfh cells.


About Sino Biological
Sino Biological is an international reagent supplier and contract research service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced with a stringent quality management system, and include unique bioreagents addressing areas such as cell therapy, stem cell, and infectious disease research. For example, Sino Biological has a wealth of viral antigens (Provir®) and corresponding antibodies, with one of the world’s Extensive collections. Sino Biological is also a well-recognized, qualified source of recombinant cytokines and high-quality GMP-grade cytokines. In addition, Sino Biological offers contract research production services for the custom development of full length, bioactive proteins and high-affinity antibodies, along with other services. To learn more about Sino Biological visit www.sinobiological.com, follow us on LinkedIn or @SinoInc on Twitter.
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