TNF-α: A Master Pro-inflammatory Cytokine

Tumor Necrosis Factor-alpha (TNF-α) is a cytokine important in nearly all acute inflammatory reactions by acting as an amplifier of inflammation. TNF-α blockade has been used worldwide to treat inflammatory conditions, e.g., rheumatoid arthritis. Targeting TNF-α to treat cancer and cardiovascular diseases is also being evaluated in clinical trials.

Sino Biological has developed a panel of high-quality recombinant TNF-α and receptor proteins to support the study of this cytokine.