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Anticancer Therapies – News and Features

Tumor microenvironment.
News

“Unexpected” Kidney Cancer Drug Resistance Mechanism Uncovered

For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwestern Medical Center’s Kidney Cancer Program sheds light
Immunofluorescence image shows macrophages (red) in human clear cell renal cell carcinoma, the most common type of kidney cancer in adults.
News

Macrophages Link Obesity to Cancer and Immunotherapy Response

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

Cancer cells.
News

Enhancing CAR-T Cell Therapies With Biodegradable Scaffolds

T-cell stimulating biomaterial that slowly biodegrades under the skin stimulates CAR-T cells in the body to improve therapeutic efficacy in an aggressive mouse tumor model.
Cancer cells.
News

Protein Discovery May Lead to Improved Treatments for Ovarian Cancers

Cleveland Clinic researchers have discovered a new location for a protein that helps ovarian cancer cells resist chemotherapy treatments and that fosters aggressive cancer stem cell growth.
Cancer cells.
News

Protein Engineering Approaches Offer Hope for Cancer Therapies

While cancer treatments have seen large improvements over the last decades, researchers are still laser-focused on developing strategies to defeat cancers, especially those that have been resistant to traditional interventions.
A digital illustration of cells.
News

“Artificial Lymph Node” May Help Train the Immune System To Kill Cancer Cells

A new study has found that implanting an “artificial lymph node” under the skin of mice may act as a hub to teach immune cells how to recognize and kill cancer cells, prolonging mouse survival and slowing tumor growth.
Drug capsules of different sizes, colors and shapes.
News

Bladder Cancer Therapy Shows Promise for Those Unresponsive to Standard Treatment

A combination of oncolytic virotherapy and an immune checkpoint inhibitor has shown promise for unresponsive bladder cancer.
Cancer cells.
News

“Molecular Portrait” Established of Key Pancreatic Cancer Gene

Researchers have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or “oncogene,” and how its activities impact pancreatic cancer outcomes.
Cancer cells.
News

New Brain Tumor Therapy Helps Immune System Recognize Cancer Cells

In a major advance for the treatment of the deadly brain cancer glioblastoma, scientists used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy drug cocktail.
Red blood cells and antibodies flow through a blood vessel.
News

Protein Complexes Work Together To Coordinate Attacks Against Immune System Invaders

Researchers have uncovered a molecular mechanism that helps the immune system coordinate its response to pathogens and regulate inflammation.
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