Cancer Genetics – News and Features

A first-of-its-kind GWAS study has identified two genetic variants linked to breast cancer in black South African women.

A new study shows that inactivating the SOX9 gene in colorectal cancer promotes tumor invasion and progression. Researchers found that low SOX9 levels correlate with poorer survival in patients.

Microscopic command centres in our bodies called primary cilia – once thought irrelevant – could be hidden switches powering cancer growth and drug resistance.

A study analyzed genetic data from over 1,400 men with testicular germ cell tumors (TGCTs) and 18,000 cancer-free controls. The findings suggest a link between TGCT risk and genetic variants affecting cell movement and shape.

A new study has revealed that FOXR2 activation occurs in multiple brain tumor types, not just CNS neuroblastoma. This discovery could improve the diagnosis, prognosis and treatment of brain tumors.

By simply tweaking some of the burn conditions, cancer risks from smoke exposure could be cut by 50%.

Researchers used mutational analysis to identify gene mutations that may drive carcinogenesis in colorectal tumors with high tumor mutation burden.

A new study, led by WashU Medicine researchers, takes a deep dive into inherited genetic mutations measured in a healthy blood sample and reports how those mutations might predispose a person to develop cancers later in life.

An innovative new approach offers the potential for transforming the genetic culprit behind pancreatic ductal adenocarcinoma's stubborn resistance to treatment into a therapeutic ally.

A new discovery at the CSHL Cancer Center could make treating "early versions" of pancreatic cancer possible.