CRISPR and Genome Editing – News and Features

An array of nanopillars that can breach the nucleus of cells without damaging the membrane could open new possibilities in gene therapy.

Researchers found that blocking somatostatin restores glucagon release in type 1 diabetes, potentially preventing severe hypoglycemia. The study highlights the relationship between pancreatic hormone-producing cells and electrical signaling.

Researchers from the Stowers Institute for Medical Research have unveiled a critical timing factor involved in regulating regeneration in killifish.

A study has revealed two distinct molecular subtypes of Crohn’s disease using organoids from adult stem cells, allowing for better understanding of the disease's mechanisms. The findings suggest treatments should be tailored based on these subtypes.

A single infusion of a new gene therapy can reduce the number of bleeding episodes by an average of 71%, according to a new study.

Technology Networks spoke with Nicola Alderson, COO at Anthony Nolan, to discuss some of the current stem cell supply challenges and learn more about how donor registries can help overcome stem cell supply chain issues.

Research at Mississippi State focuses on enhancing protein content in rice and soybean crops through gene editing. This approach aims to combat global protein deficiency, improve nutrition, and promote sustainable agricultural practices.

Researchers at Weill Cornell Medicine developed a CRISPR-based mouse model to track prostate cancer metastasis. By using genetic barcoding, they mapped the spread of cancer cells and identified patterns that mirror human cancer behavior.

Researchers have optimized the small protein TnpB to enhance gene editing efficiency, achieving up to 75.3% success in mouse models. This advancement could lead to effective treatments for genetic diseases.

A new preclinical model using CRISPR, an advanced technology that allows scientists to cut and edit genes, has given researchers and their colleagues a deeper insight into how prostate cancer spreads or metastasizes.