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RNA-Seq – News and Features

Gloved hands draw medicine into a syringe from a glass vial.

Liver Tumor Microproteins Could Lead to Cancer Vaccines

A study has identified a group of small molecules that could be key to developing cancer vaccines. These microproteins are very small proteins expressed only by tumor cells and can activate immune cells against the tumor.
A white and red virus particle on a black background.

Hepatitis C Leaves Lasting “Scars” On the Immune System Even After Treatment

New research has provided insights into the lasting effects of chronic Hepatitis C virus (HCV) infection on the immune system.
A patient in a hospital gown receives treatment through an IV.

AI Model Can Select Treatments To Help Improve Cancer Therapy Responses

A new artificial intelligence tool that can help to select the most suitable treatment for cancer patients has been developed by researchers at The Australian National University.
A stem cell dividing in two with other cells and DNA helices in the background

Unmasking the True Identity of Gut Stem Cells

Columbia researchers have found that Lgr5+ cells descend from the gut’s true stem cells. This case of mistaken identity may explain why regenerative medicine has not lived up to its promise.
A man holding a clump of his hair and holding his head

Targeting an Ancient Biological Stress Response Could Help Prevent Hair Loss

Activation of an ancient biological stress response has been linked to a proliferative block in the human hair follicle. Researchers suggest that targeting this stress response could be used to help maintain hair follicles and treat hair loss.
A 3D model of a human brain.

RNA Editing Differs in Living vs Postmortem Brains

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.
Red and blue frog on the ground.

Frogs' Light-Sensing Proteins Have Evolved With Surprising Diversity

Opsins are responsible for many biological functions, like regulating circadian rhythms. Research into the evolution of nonvisual opsins in frogs has found that most modern species examined retained a shocking number of these proteins.
Human immune cells (nucleus: blue, cell boundary: red) with Mycobacterium tuberculosis (green) in the collagen hydrogels.

New 3D Model Speeds Up TB Drug Testing

Researchers from the Department of Bioengineering (BE), Indian Institute of Science (IISc), have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment.
A gloved hand placing a vial inside an LC-MS instrument.

Mass Spectrometry Imaging in Pharmaceutical Development

In this article, we explore how mass spectrometry imaging technology is evolving into a high-resolution spatial biology toolset to transform drug discovery and development.

Celiac Drug Shows Promise in Early Trial

A recent study investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease. Previous tissue studies have shown that the ZED1227 transglutaminase 2 inhibitor prevents gluten-induced intestinal damage.