RNA-Seq – News and Features

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Commonly Prescribed Anti-Swelling Drug Suppresses Immune Response
While controlling swelling caused by brain cancer is important, a new study shows that a commonly prescribed anti-swelling drug suppresses the immune system for weeks after dosage, inhibiting the body’s ability to fight the cancer.

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Why Is Brain Cancer So Resistant to Immunotherapy?
Researchers find four coordinated gene expression programs in immune cells from glioma tumors, including two that could lead to immunotherapy resistance.

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A New Framework for Understanding Metabolism
New research uses genomics to provide insights into how organisms adjust their metabolism, taking a step toward understanding the complex functions of the metabolic network.

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Case Study Reveals Rare Side Effect of CAR T-Cell Therapy
A new study from researchers at the University of Leipzig Medical Center and collaborators, has discovered a rare but serious side effect of CAR T-cell therapy in a 63-year-old patient.

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Myocarditis Differs Depending On the Cause
A group of Berlin researchers in collaboration with international scientists have found differences in heart inflammation caused by COVID-19, anti-COVID-19 vaccination, and non-COVID-19 myocarditis.

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New Aspect of Rett Syndrome’s Pathogenesis Discovered
New research brings scientists one step closer to understanding Rett Syndrome, a rare genetic disease that affects 1 in 10,000 newborn girls.

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Sponge-Like Implant Helps Identify MS Treatment in Mice
University of Michigan researchers developed a sponge-like implant that tracks early immune activity in MS-like disease. Using insights from the implant, they designed nanoparticles that halted or reduced symptoms in mice.

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AI Sheds Light on 300 Million Years of Brain Evolution
Deep learning models have shed light on how genetic switches controlling gene activity define brain cell types across species.

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Landmark Atlas Reveals How Aging Breast Tissue Shapes Breast Cancer Risk
Researchers at The Jackson Laboratory created an aging breast tissue atlas, revealing how genetic and molecular shifts may increase cancer risk. Changes in epithelial, immune and stromal cells create a tumor-friendly microenvironment.

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Bird Brains Evolved Independently From Mammals
New studies show that bird and mammal brains evolved separately, with distinct genetic programs and developmental mechanisms. Researchers found that these species developed similar functions through different evolutionary paths.
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