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Screening Strategies in Drug Discovery – News and Features

An outline of a brain with AI and Chat GPT written across it.
News

Scientists Code ChatGPT To Design New Drug Compounds

Generative AI like ChatGPT can do more than help write emails — it can also design new drugs to treat disease, reports a new study that shows how AI can generate unique molecular structures as potential drugs.
Two glass beakers holding NMR glass tubes.
Article

Benchtop NMR Breaks New Ground

Explore how recent technical advances in the design and construction of NMR instrumentation have eliminated practical issues that faced scientists whose experiments would benefit from the power of the technique, but who needed the speed and convenience of analysis unachievable with traditional high-field instruments.
Bacteriophages.
News

Bacterial Immune System Makes Them More Susceptible to Antibiotics

A research team has now shown how the immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.
Scientist with an assay plate.
News

3D Atherosclerosis Model Enables High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease.
A red and blue capsule broken in two, revealing drug molecules.
News

Using AI To Accelerate Novel Drug Design

Researchers have developed a platform that combines automated experiments with AI to predict how chemicals will react with one another, which could accelerate the design process for new drugs.
A lab worker.
News

New Material Gulps Down Hydrogen, Spits It Out To Protect Fusion Reactor Walls

University of Wisconsin–Madison engineers have used a spray coating technology to produce a new workhorse material that can withstand the harsh conditions inside a fusion reactor.
Pipette tips transferring liquid to a multi-well plate.
Article

Revolutionizing High-Throughput Drug Screening With AI and Organoids

Thanks to the rise of AI, HTS for drug discovery is taking a more intelligent, computational approach, with tools that allow scientists to pinpoint the most promising drug candidates faster. Explore how this evolution will be further enhanced by a shift from 2D to 3D biological models such as organoids.
Two microfluidic chips
Article

A Guide to Organ-on-a-Chip

By replicating the microenvironment of human organs within microscale devices, OOAC technology has emerged as a powerful tool for understanding human physiology and disease mechanisms with unparalleled precision.
Representation of cells.
Industry Insight

Maximizing Cell Line Productivity and Efficiency

In this interview, Dr. Tabitha Bullock tells us about some of the key considerations in cell line development and how advances in technology are improving the efficiency and productivity of cell lines.
Oil droplets.
News

High-Throughput Mass Spectrometry Platform Enables In Situ Screening of Fatty Acid-Producing Strains

A high-throughput mass spectrometry platform has enabled the in situ screening of fatty acids, showing it to be an efficient tool for fatty acid biomanufacturing.
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