Structural Biology – News and Features

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CIN Signatures Predict Chemotherapy Resistance
A new genomic test has been developed to accurately predict whether a patient’s cancer will resist common chemotherapy treatments.

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Machine Learning Algorithm Predicts Protein-Water Contributions to Drug Binding
Water molecules represent a powerful but largely underappreciated foothold in drug binding studies. See how ColdBrew can provide accurate water displacement predictions for protein structures, providing a clearer landscape for drug discovery.

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How Mitochondrial Energy Metabolism Is Controlled
Researchers at the University of Cologne have identified the key mitochondrial protein AIFM1 as a central coordinator of cellular energy production.

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Biophysics Reveals How Proteins and Nanoparticles Interact
To reveal the science behind the protein–nanoparticle interaction and its implications for human health, a team of researchers conducted a series of spectroscopy-based experiments.

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Ancient Golden Silk Used by Emperors Brought Back to Life
Scientists have recreated an ancient golden silk fiber used historically by emperors and popes. The recreation could open the door to more sustainable, dye-free fabrics and materials.

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Characterizing Complex Intracellular Signaling To Find Cancer Drug Targets
A complex signaling process involving paxillin, a focal adhesion protein, may be vulnerable to cancer therapy despite its fluid state.

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How Did Animal Multicellularity Originate?
New research provides insights into how a sophisticated mechanism for cell division contributed to the evolution of multicellular life.

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AI Approach Could Make Designing Proteins for New Medicines Easier
Scientists have created an AI approach that could make designing proteins for new medicines easier. This new AI approach outperforms current methods for "inverse protein folding" – a critical part of the process of creating new proteins.

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Improved Imaging Technique Could Help Boost Lifespan of Next-Gen Batteries
The next generation of batteries may get a lifespan boost, thanks to a new imaging technique that can provide high-resolution images of lithium-metal batteries as they charge.

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Protein Structure Discovery Unlocks Disease Insights
Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology — potentially opening the door for better-designed therapeutics.
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