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Structural Biology – News and Features

Microbes of different shapes, sizes and colors.

Climate Change May Threaten Freshwater Bacteria With Limited Adaptability

Freshwater bacteria crucial to ecosystem functioning may not be able to adapt quickly enough to survive climate change.
An NMR Spectrometer autosampler.

High Pressures Reveal Novel Structural Features in Proteins

3,000 bar of pressure reveals structural features of proteins that are too volatile to be observed under normal conditions.
A cell dividing.

Scientists Discover Protein Complex That Controls Cell Division

Researchers have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of certain diseases.
A cell dividing.

Researchers Track “Doubling” in Origin of Cancer Cells

Researchers have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer.
Bacteria bloom on a petri dish.

Bacteria Use a Protein Complex To Enhance Blockage of Phage Replication

The molecular assembly of a common anti-phage system employed by bacteria has been described in a new study.
Illustration of a human form

Dissecting the Proteome To Understand Disease

Proteomics provides insights into the regulation of biological processes and mechanisms of disease. In this article, we explore approaches scientists are using to find early markers of disease, new drug targets and strategies to overcome resistance to treatments.
A person sits next to a pile of photographs.

Memory Formation Mechanism Requires DNA Flexibility

Researchers have uncovered a novel mechanism underlying memory formation that involves rapid changes to DNA structure.
The new technique scan the surface of molecules, tracking their movement.

New Technique Generates “Movies” of Changing Protein Structures

Researchers have developed a powerful, new technique to generate “movies” of changing protein structures and speeds of up to 50 frames per second.
A bacteriophage with bacteria in the background.

Researchers Discover Mechanism Behind How Phages Disarm Pathogenic Bacteria

Researchers have uncovered how bacteriophages disarm antibiotic-resistant bacteria, opening doors to the possibility of new treatment methods.
Three in-focus cells with many more out of focus behind them.

Starved Cells Divert Protein Transport Stations to Cellular Recycling Centers

A new study details how nutrient-starved cells break down protein transport stations to deal with stressful conditions.