The Immune System – News and Features

New research from the University of Copenhagen and NTU Singapore reveals that RNA damage, rather than DNA, plays a primary role in the skin’s immediate response to UV radiation. This RNA damage activates the ribotoxic stress response.

A new storage technique can keep protein-based drugs and vaccines stable without keeping them cold.

Researchers discovered that inflammasomes prevent cancer in blood stem cells by regulating proliferation and suppressing oncogenes like Ras. This protective mechanism involves cleaving tumor necrosis factor (TNF) receptors in the bone marrow stroma.

A study found that 85% of Long Covid patients had multiple Covid infections, highlighting re-infection as a key risk factor. Vaccination prior to initial infection significantly reduced the likelihood of developing Long Covid.

Researchers from Mass General Brigham and Washington University have found that Xenon gas inhalation reduces neuroinflammation, brain atrophy and amyloid and tau pathologies in Alzheimer’s mouse models.

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site structure that regulate viral protein synthesis. These findings highlight ribosome pausing as a key mechanism.

Two new studies led by researchers at Washington University School of Medicine in St. Louis have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.

Researchers from UW Medicine and the Technical University of Denmark have developed computationally designed proteins to neutralize toxins in elapid snake venom. These proteins target three-finger toxins.

A study reveals that aerobic exercise significantly reduces Alzheimer’s disease markers, including tau tangles, amyloid plaques, and iron buildup in the brain. The findings highlight how exercise enhances brain health.

Garvan Institute researchers discovered how chronic hepatitis C virus (HCV) infections lead to autoimmune diseases like cryoglobulinemic vasculitis. By identifying rogue B cell clones caused by persistent antibody clustering and mutations.