The Immune System – News and Features

A new analysis shows the two major CLL subtypes likely arise from distinct points in B cell development. Mutated CLL resembles mature memory B cells, while unmutated CLL aligns with an earlier germinal centre stage.

Changing the high-risk version of the APOE gene to the protective form has been shown to improve multiple aspects of Alzheimer's pathology.

Growing evidence links skeletal muscle function to cognitive health. Research takes this evidence to the next level, revealing that the key to fighting AD may lie not just in the brain – but also in our muscles.

Researchers uncover a unique gut immune pathway that produces long-lasting IgA antibodies, offering new strategies for durable mucosal vaccines.

Discover how a pomegranate-derived compound rejuvenates the immune system of middle-aged adults, with applications in fighting infection, aging and cancers.

Researchers in Singapore have developed a dual RNA therapy that silences mutant KRAS and activates immune signalling, delivered through red blood cell-derived vesicles. In laboratory models, the approach reduced tumour growth.

A treatment that could protect premature babies from brain damage showed promise in a complex prenatal brain model.

An analysis of nearly 6,000 newborns found that genetic susceptibility to schizophrenia, autism and ADHD is linked to distinct DNA methylation patterns at birth. The strongest signals involved immune-related genes tied to schizophrenia risk.

Counties in Pennsylvania that contained or were near cultivated cropland have significantly higher melanoma rates, a new study has found.

Single-cell technologies provide insights into health, but data integration can be challenging. Discover how researchers have designed Coralysis to address this!