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The Immune System – News and Features

Hospital beds on a ward.

Cell-Based Lymphoma Therapy Shows Promise in Trial

CAR-T cell therapy causes tumors to shrink or disappear, but if this CAR-T treatment fails, the median survival time after relapse is about six months. Now, a phase 1 clinical trial has found that a new CAR-T cell therapy significantly improved these patients’ outcomes.
Immune cells attacking a cancer cell.

Researchers Create Novel Cell Type That Kills Cancer Cells in Research Models

Researchers have combined the genetic components of four types of cells to make a powerful new cell type, Co-STAR (Co-stimulatory Synthetic T-cell receptor and Antigen Receptor) cells. These cells were able to produce a sustained anti-tumor response against human cancer cells in laboratory studies.
A person with gloved hands holding a rack of blood test vials.

Researchers Discover an Immune Defect in Lupus and a Possible Way To Reverse It

Researchers have uncovered a molecular defect that promotes the pathologic immune response in lupus, and have shown that reversing this defect could treat the disease.
Gloved hands draw medicine into a syringe from a glass vial.

Liver Tumor Microproteins Could Lead to Cancer Vaccines

A study has identified a group of small molecules that could be key to developing cancer vaccines. These microproteins are very small proteins expressed only by tumor cells and can activate immune cells against the tumor.
A white and red virus particle on a black background.

Hepatitis C Leaves Lasting “Scars” On the Immune System Even After Treatment

New research has provided insights into the lasting effects of chronic Hepatitis C virus (HCV) infection on the immune system.
Pink cells.

Long-Lived Proteins Are Essential to Egg Cell Maintenance

Long-lived proteins in egg cells appear to help maintain fertility for as long as possible.
Two cytotoxic T cells attack a cancer cell.

Stem Cell-Derived Therapy Shows Early Promise for Resistant Liver Cancer

An innovative new stem cell-derived therapy could be used to better target and treat the most common form of liver cancer.
Four pink floating cancer cells adhered together.

Implantable LED Device Shows Promise Using Light in Deep-Seated Cancer Models

Scientists have devised a wireless LED device that, when combined with a light-sensitive dye, destroys cancer cells and mobilizes the immune system’s cancer-targeting response.
A small pile of peanuts on a wooden dish.

Soda Prebiotic Could Treat Food Allergies, Say Researchers

A new study has identified a potential new treatment for food allergies in inulin, a naturally occurring plant fiber commonly used as a supplement, a prebiotic in soda and a replacement for sweeteners.
Cell images showing SARS-CoV-2 spike protein-encoding RNA present in the tissues of long COVID patients

Imaging Study Reveals Viral RNA Persists for Years in Tissues of Long COVID Patients

PET imaging reveals long COVID patients can possess leftover SARS-CoV-2 RNA in the gut years after infection. The findings add to mounting evidence that viral persistence and sustained immune activation are key factors underpinning long COVID.