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Therapeutic Antibodies – Multimedia

Automated Switching Between Peptide and Glycan Mapping content piece image
App Note / Case Study

Automated Switching Between Peptide and Glycan Mapping

Glycan and peptide mapping are key analytical methodologies for the structural characterization of therapeutic proteins such as monoclonal antibodies (mAbs).
Preclinical Quantification of Trastuzumab in Rat Plasma content piece image
App Note / Case Study

Preclinical Quantification of Trastuzumab in Rat Plasma

In quantifying therapeutic peptides and proteins in biological matrices, traditional ELISA-only based techniques can suffer from high variability, narrow dynamic range, problems with selectivity and typically cannot use internal standards.
Biopharmaceuticals: What They Are and How They Are Made With Professor Andrew Zydney content piece image
Video

Biopharmaceuticals: What They Are and How They Are Made With Professor Andrew Zydney

In less than 10 minutes, Professor Andrew Zydney covers: What are biopharmaceuticals? How do they differ from traditional small-molecule pharmaceuticals? How are they made? What factors might influence the high cost of biopharmaceuticals?
Antibody-Based Therapeutics Against Cancer: Emerging Targets and Research Tools content piece image
Video

Antibody-Based Therapeutics Against Cancer: Emerging Targets and Research Tools

Speaking at The Landscape of Cancer Research 2021 online symposium, Tianzi Li delivered her talk on the discovery of novel targets and the use of antibodies in cancer therapy.
A Roadmap to Antibody Drug Discovery content piece image
Infographic

A Roadmap to Antibody Drug Discovery

In recent years, therapeutic antibodies have become the predominant class of new drugs developed in order to combat different diseases including cancers and autoimmune diseases among others. Antibody drug discovery does not come without its challenges including screening, characterization and target identification.
Controlling the Half-Life of Pathological IgG and Therapeutic Antibodies content piece image
App Note / Case Study

Controlling the Half-Life of Pathological IgG and Therapeutic Antibodies

Various autoimmune diseases (e.g., myasthenia gravis) are mediated by IgG autoantibodies. To address this mechanism of autoimmunity, researchers are exploring the therapeutic use of FcRn inhibitors in an effort to decrease the pathogenesis of IgG and develop new therapies.
Therapeutic Antibodies content piece image
Infographic

Therapeutic Antibodies

In this infographic, we explore the pipeline of therapeutic antibody discovery, development and manufacturing, highlighting key advancements throughout.
New Electron Microscopy Technique Could Shortcut Development of Vaccines and Antibody Therapies content piece image
Video

New Electron Microscopy Technique Could Shortcut Development of Vaccines and Antibody Therapies

Scientists at Scripps Research have devised a method that may be able to shortcut one of the big steps in modern vaccine development.
Mannose Glycans Content Screening for Human-mAb Samples content piece image
App Note / Case Study

Mannose Glycans Content Screening for Human-mAb Samples

Glycosylation refers to the formation of linkages with glycosyl groups, covalently attaching a carbohydrate to another molecule. Antibody glycosylation is critical due to the role carbohydrates play in modulating effector functions which affect safety and efficacy of therapeutic antibodies.
Therapeutic Antibody Engineering: Past, Present and Future content piece image
Listicle

Therapeutic Antibody Engineering: Past, Present and Future

Download this free listicle to learn more about the current scope and future prospects for therapeutic antibody engineering.
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