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Therapeutic Antibodies – Multimedia

Convenient Customization of Your Cation Exchange Analysis content piece image
App Note / Case Study

Convenient Customization of Your Cation Exchange Analysis

Therapeutic monoclonal antibodies (mAbs) are highly heterogeneous molecules due to being composed of a large number of variants. When the variants are present in the pharmaceutical protein, it is possible their biological activity could be altered.
Convenient and Reliable Analysis of Antibody–Drug Conjugates content piece image
App Note / Case Study

Convenient and Reliable Analysis of Antibody–Drug Conjugates

Antibody–drug conjugates (ADCs) are monoclonal antibodies to which a cytotoxic small molecule drug is chemically linked. The structures of ADCs are more complex than their corresponding antibodies.
Preparation of Buffers and Solutions for Therapeutic Antibody Analysis content piece image
App Note / Case Study

Preparation of Buffers and Solutions for Therapeutic Antibody Analysis

Antibodies are subject to instability issues due to chemical and physical instabilities and these effects can change the pharmacokinetics of the antibody. For this reason, produced antibodies must be thoroughly tested before they can be applied for treatment of patients.
Your Guide to Multiple Attribute Methodology (MAM) content piece image
App Note / Case Study

Your Guide to Multiple Attribute Methodology (MAM)

In biotherapeutic process development, evaluating and tracking potential product quality attributes (PQAs) is crucial to ensure quality, safety, and efficacy.
Your Guide to mAb Variants content piece image
App Note / Case Study

Your Guide to mAb Variants

Antibody-based derivatives have received increased attention as therapeutics in biopharmaceutical development because of their unique capacity to engage multiple molecular targets, engage immune effector cells or even penetrate tissues previously inaccessible to conventional mAbs.
Key Developments in Cancer Immunotherapy Over the Last Decade content piece image
Listicle

Key Developments in Cancer Immunotherapy Over the Last Decade

Download this list to explore current immunotherapeutic strategies, recent regulatory approvals and the future of cancer therapy.
Applications of Single-Cell Sequencing content piece image
Listicle

Applications of Single-Cell Sequencing

Over recent years, single-cell sequencing has become a method ubiquitously used across several different areas of biological research. Why have so many researchers so rapidly adopted this relatively novel set of techniques and how can they be applied?
Accelerating Antibody Drug Development With Affinity Purification content piece image
Poster

Accelerating Antibody Drug Development With Affinity Purification

The changing landscape for antibody-derived therapeutics, such as bi-specific monoclonal antibodies, Fab fragments and Fc-fusion proteins brings new purification challenges in the downstream processing of these molecules. Standard chromatography resins, such as Protein A, may not result in the most efficient purification process.
Achieve Robust Quantification of Antibody-Dependent Cellular Phagocytosis content piece image
App Note / Case Study

Achieve Robust Quantification of Antibody-Dependent Cellular Phagocytosis

Download this app note to discover a high-throughput, multiplex assay that can profile large libraries of mAbs for their effects on antibody-dependent cellular phagocytosis in minimal time.
Introducing the Antibody content piece image
Infographic

Introducing the Antibody

Antibodies are a vital part of the immune system, playing a key role in our ability to fight infection and in the efficacy of vaccinations. However, that’s not where their utility ends. Find out about what antibodies are, where they come from, how they function and how science is putting them to work in the laboratory.
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