This animation depicts how Cas13 — a CRISPR-associated protein — may be adapted to detect human disease. This new diagnostic tool, called SHERLOCK, targets RNA (rather than DNA), and has the potential to transform research and global public health.
Produced by: McGovern Institute for Brain Research at MIT.
In collaboration with: Broad Institute of MIT and Harvard.
With special thanks to :Feng Zhang (McGovern Institute, Broad Institute), Omar Abuddayeh (McGovern Institute), Jonathan Gootenberg (McGovern Institute), Ian Slaymaker (Broad Institute) and Sabbi Lall (McGovern Institute).
Animation by: Sputnik Animation
Narration by: Julie Pryor (McGovern Institute)
Addition footage by: Scott Sassone (Broad Institute) and Sabeti Lab (Broad Institute, Harvard University)
SHERLOCK: A CRISPR Tool to Detect Disease
Video Jan 15, 2019 | Video by The McGovern Institute for Brain Research at MIT
Recommended Videos
From the smallest single-celled organism to the largest creatures on Earth, every living thing is defined by its genes. With recent advancements, scientists can change an organism’s fundamental features in record time using gene editing tools such as CRISPR. But where did this medical marvel come from and how does it work? Andrea M. Henle examines the science behind this new technology.
WATCH NOWLike what you just watched? You can find similar content on the communities below.
Cell Science Genomics Research Immunology & MicrobiologyTo personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free
LOGIN SUBSCRIBE FOR FREE