We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy


SHERLOCK: A CRISPR Tool to Detect Disease

Video   Jan 15, 2019 | Video by The McGovern Institute for Brain Research at MIT


This animation depicts how Cas13 — a CRISPR-associated protein — may be adapted to detect human disease. This new diagnostic tool, called SHERLOCK, targets RNA (rather than DNA), and has the potential to transform research and global public health.

Produced by: McGovern Institute for Brain Research at MIT.

In collaboration with: Broad Institute of MIT and Harvard.

With special thanks to :Feng Zhang (McGovern Institute, Broad Institute), Omar Abuddayeh (McGovern Institute), Jonathan Gootenberg (McGovern Institute), Ian Slaymaker (Broad Institute) and Sabbi Lall (McGovern Institute).

Animation by: Sputnik Animation

Narration by: Julie Pryor (McGovern Institute)

Addition footage by: Scott Sassone (Broad Institute) and Sabeti Lab (Broad Institute, Harvard University)

More Information

Recommended Videos

Unlocking the Protein Structure of Coronavirus


The novel coronavirus sweeping the globe packs 27 proteins, each adopting a unique, often incredibly complex 3D structure. Each protein is part of the molecular toolkit that the virus uses to infect, replicate, and spread. Understanding the proteins' structures provides a blueprint for drug designs.


Air Pollution Over China Dropped in January, Rebounding in March - Satellite Data


A drop in nitrogen dioxide emissions correlated to the nationwide quarantine in China in January 2020. Two months later the emissions are increasing.


Whole Genome Sequencing for Infectious Disease Outbreaks


This video describes how whole genome sequencing is used to track pathogens as they spread from person to person on the path to a foodborne or infectious disease outbreak.



Like what you just watched? You can find similar content on the communities below.

Cell Science Genomics Research Immunology & Microbiology

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free