Latest On-Demand Webinars & Online Events

This talk will cover two complementary technologies for measuring metabolic flux: Seahorse XF analyzers and liquid chromatography-mass spectrometry (LC/MS) qualitative flux analysis. Both technologies provide important insights into the rates of metabolic reactions within cells, with Seahorse XF measurements providing cellular resolution, and LC/MS qualitative flux measurements providing molecular resolution.

Suitable quantification standards were generated by derivatized with labelled 13C2-dansyl chloride and 13C2dansylhydrazine. The derivatization of the standards and the urine sample was performed using a PAL RTC autosampler in-line to column-switching LC-HRMS analysis with data independent acquisition (SWATH-MS). The combination of dual DIL with SWATH-MS acquisition enables post-identification of unknown metabolites and quantitation at precursor (MS1) and specific tag fragment (MS2) levels.

These talks from Brurker Daltonics will discuss the PASEF, dia-PASEF and prm-PASEF methods, and how these methods allow researchers to perform proteomics faster, with better depth of coverage. They will also discuss new, high-performance technologies for improving spatial resolution, sensitivity and specificity of MALDI IMS. Both talks will cover some of the latest applications of these methods and technologies.

We have been using fast scanning TripleTOF systems to analyze a variety of post-translational modifications (PTMs) using both data-independent acquisitions (DIA) and more recently multiple reaction monitoring-high resolution (MRM-HR) to identify, characterize and quantify PTM-containing peptides in a high-throughput format. While rich information has been obtained using traditional CID fragmentation approaches, many of the modifications we study are highly labile and difficult to characterize.

In this session, Pall Corporation and Evello International will share their best practices on how to optimize your extraction and filtration process.

In this webinar, Kristina Schwamborn, associate professor in the Institute of Pathology at the Technical University of Munich, will discuss how MALDI-IMS can overcome the limitations of other approaches in the discovery and identification of new classifying marker molecules and profiles.

Single domain antibodies (sdAbs) have seen a tremendous uptake in various fields. Attend this webinar to discover the versatility of sdAb technology in antibody drug development and to explore various analytical methods developed using sdAbs.

Watch this webinar to learn about benchmarking of various approaches for complete sequencing of the SARS-CoV-2 genome as well as characterization of intrahost viral diversity and evolution, and the detection of low-frequency viruses in a host's SARS-CoV-2 population.

Discover ways to get the most out of your PCR and improve lab productivity as well as learn how to avoid typical PCR mistakes and troubleshoot PCR issues when they arise.

This virtual conference was held to provide an opportunity to share the most recent scientific advancements in the fight against SARS-CoV-2. Watch on demand to learn more about dissecting host-pathogen biology and interactions as well as vaccine and therapeutic development strategies.