Latest On Demand Webinars
Gas Safety in Your Laboratory
Bulk gas supply in the form of liquid nitrogen dewars and cylinders present laboratories with safety risks stemming from the frequent need to handle and manage gas supplies. In this webinar, we will discuss the benefits of instead using gas generators for your laboratory gas supply in terms of safety, convenience and the potential reduction of overheads compared to cylinders or dewars.
Retinal Organoids as an Emerging Tool for Drug Discovery
Human induced pluripotent stem cell (iPSC)-derived retinal organoids are an emerging tool for the study of retinal development, disease modeling and drug discovery.
Next-Generation Multiomics for Single-Cell and Spatial Profiling
Groundbreaking discoveries require innovative tools. Single-cell and spatial sequencing technologies have transformed our understanding of biology by letting us profile and visualize cell and tissue heterogeneity with powerful resolution.
Cytokine Profiles and Personalized Therapeutics in COVID-19 Patients
Recent observations by Prof. Gorochov’s team at the CIMI Research Centre suggest that there are at least two distinct types of cytokine signatures induced by SARS-CoV-2 infection.
Making Spatial Analysis Accessible to the Community
This talk will serve as a guide through on how the technology has evolved, how the protocol is run at NGI and the service that they provide their users.
Measuring Metabolic Flux with Cellular and Molecular Resolution: Combining Seahorse XF and LC/MS Technologies for Comprehensive Cellular Analyses
This talk will cover two complementary technologies for measuring metabolic flux: Seahorse XF analyzers and liquid chromatography-mass spectrometry (LC/MS) qualitative flux analysis. Both technologies provide important insights into the rates of metabolic reactions within cells, with Seahorse XF measurements providing cellular resolution, and LC/MS qualitative flux measurements providing molecular resolution.
Automated Parallel Derivatization of Metabolites with SWATH-MS Data Acquisition
Suitable quantification standards were generated by derivatized with labelled 13C2-dansyl chloride and 13C2dansylhydrazine. The derivatization of the standards and the urine sample was performed using a PAL RTC autosampler in-line to column-switching LC-HRMS analysis with data independent acquisition (SWATH-MS). The combination of dual DIL with SWATH-MS acquisition enables post-identification of unknown metabolites and quantitation at precursor (MS1) and specific tag fragment (MS2) levels.
Latest Applications of 4D-Proteomics using the timsTOF Pro and recent developments in ultra-high sensitivity applications
These talks from Brurker Daltonics will discuss the PASEF, dia-PASEF and prm-PASEF methods, and how these methods allow researchers to perform proteomics faster, with better depth of coverage. They will also discuss new, high-performance technologies for improving spatial resolution, sensitivity and specificity of MALDI IMS. Both talks will cover some of the latest applications of these methods and technologies.
Challenges and Opportunities to Quantify Post-translational Modifications using Novel Proteomic Workflows and Approaches
We have been using fast scanning TripleTOF systems to analyze a variety of post-translational modifications (PTMs) using both data-independent acquisitions (DIA) and more recently multiple reaction monitoring-high resolution (MRM-HR) to identify, characterize and quantify PTM-containing peptides in a high-throughput format. While rich information has been obtained using traditional CID fragmentation approaches, many of the modifications we study are highly labile and difficult to characterize.
Extraction E2E: Why Filtration is a Critical Step in Cannabis Oil Processing
In this session, Pall Corporation and Evello International will share their best practices on how to optimize your extraction and filtration process.