Effective Nuclei Isolation From Tissue for Single-Nucleus Sequencing
In this webinar, we present a standardized workflow solution, including easy and automated nuclei extraction and isolation for reproducible single-nucleus sequencing analysis.
Assessment of Biotherapeutics Quality Attributes Leveraging a Novel Fragmentation Technique
The novel fragmentation technique, electron activated dissociation (EAD) of the ZenoTOF 7600 system (SCIEX), was employed for peptide mapping of a multispecific monoclonal antibody (mAb) as well as IgG1 and IgG4 mAb samples. A specific focus was put on assessing challenging PTMs, such as glycosylations, amino acid isomers and the localization of a sulfation on a singly charged peptide.
Opportunities and Challenges of Blood-Based Biomarkers in Alzheimer's Disease
In this webinar, our expert speaker, Professor Lei Liu, Assistant Professor of Neurology from Harvard Medical School will discuss strategies in developing an ultrasensitive immunoassay* to measure oligomeric amyloid β in human plasma precisely.
Mapping Gene Expression Signatures in the Heart and Lungs of Patients with COVID-19
These technologies can help identify new strategies to enhance myocardial repair and regeneration through target validation and manipulation.
Developing High Content Imaging Assays for Chronic Kidney Disease
This webinar will focus on the development of HCS assays for CKD. Assays to monitor the dynamics of TNF signaling in human kidney podocytes will be explored, together with assays for ER stress and apoptosis in diabetic nephropathy.
New Sample Preparation Strategies for MALDI Imaging of Clinical Samples
A second challenge is that most clinical tissue samples are banked as formalin fixed, paraffin embedded tissue specimens, which present difficulties for the detection and imaging of biomolecules. In this webinar, we will present new sample preparation strategies for overcoming these issues and producing high quality MSI data.