Principle of Mitochondrial Toxicity Assessment
Principle of Mitochondrial Toxicity Assessment Using Agilent Seahorse XF Solution
Mitochondrial toxicity is a common issue in therapeutic development, as drugs can disrupt mitochondrial function in many ways. Having a method to directly measure mitochondrial oxygen consumption to specifically and sensitively indicate drug induced mitochondrial toxicity is therefore critical.
Download this whitepaper to learn more about:
- Mitochondrial toxicity assay design
- Screening and dose-response analysis
- Considerations for data interpretation