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Principle of Mitochondrial Toxicity Assessment

Principle of Mitochondrial Toxicity Assessment Using Agilent Seahorse XF Solution

Mitochondrial toxicity is a common issue in therapeutic development, as drugs can disrupt mitochondrial function in many ways. Having a method to directly measure mitochondrial oxygen consumption to specifically and sensitively indicate drug induced mitochondrial toxicity is therefore critical.

Download this whitepaper to learn more about:

  • Mitochondrial toxicity assay design
  • Screening and dose-response analysis
  • Considerations for data interpretation
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