New Crystal Structure of (Ph)PINK1 Aids Understanding of Early Onset Parkinson’s

Article

Scientists have determined the crystal structure of PhPINK1 bound to it's substrate ubiquitin. Mutations of PINK1 are associated with early onset Parkinson's disease and it is expected that this information will help the design of Parkinson's therapeutics.

Read more

Spectroscopic Techniques for Food Analysis to Combat Adulteration and Fraud

Article

Food fraud takes many forms, including adulteration, package tampering, outright counterfeiting of products or ingredients, mislabeling, intentional use of illegal or substandard ingredients, manufacturing shortcuts to lower production costs, and many others. Thanks to modern technology, detecting food fraud is mostly an analytical chemistry exercise, with choice of methodology depending on the quality attribute the food detective is looking for.

Read more

The All New Affinity ITC - Perfected ITC Automation

Video

While others have attempted ITC automation, leading to bent syringes and imperfect data, TA Instruments has perfected it with the all new Affinity ITC!

Watch Now

From the lab to the boardroom: An interview with Darlene Solomon Ph.D.

Life In Science

We spoke to Darlene to learn about her reasons for studying science, how she transitioned away from the lab and some of her proudest achievements at Agilent.

Read more
Targeted Antisense Treatment of APOE4 Reduces Alzheimer's Damage

Targeted Antisense Treatment of APOE4 Reduces Alzheimer's Damage

News

Novel antisense oligonucleotide interferes with the instructions for building the APOE protein and reduces pathophysiology of AD.

Read more
 
Sources of Environmental Vanadium
News

High vanadium concentrations have poorly documented but potentially negative consequences for human health. This study explores the biogeochemical cycle of vanadium including the contribution of human activities to the amount in the environment.

Read more

Blueprints for Anti-cancer Drugs Identified in Bacterial Genomes
News

Scientists have now brought the family of LNM molecules even closer to clinical testing by “mining” the information stored in bacteria genomes. Their research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

Read more

Novel Lenses Enable X-ray Microscopy with Record Resolution
News

Scientists have developed novel lenses that enable X-ray microscopy with record resolution in the nanometre regime. Using new materials, the research team has perfected the design of specialised X-ray optics and achieved a focus spot size with a diameter of less than ten nanometres.

Read more