New Crystal Structure of (Ph)PINK1 Aids Understanding of Early Onset Parkinson’s

Article

Scientists have determined the crystal structure of PhPINK1 bound to it's substrate ubiquitin. Mutations of PINK1 are associated with early onset Parkinson's disease and it is expected that this information will help the design of Parkinson's therapeutics.

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Milestones in Microfluidics

Quiz

Take our quiz to see how much you know about some of the key developments in the history of microfluidics.

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7 Microfluidic Highlights of 2017

List

In this list, we take a look at 7 promising microfluidic developments from the past year.

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Small Compound Able to Stave Tumor and Stop its Growth

News

Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital nutrient glutamine.

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Arrow Poison Potential Male Birth Control

Arrow Poison Potential Male Birth Control

News

Women have many options for oral contraceptives that are safe, effective and reversible, but despite decades of research, men have none. Now, scientists report a rat study that shows they finally have a good lead for a male birth control pill. It's based on ouabain, a plant extract that African warriors and hunters traditionally used as a heart-stopping poison on their arrows.

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Meteorite Dust Charts History of the Solar System
News

Using a state-of-the-art mass spectrometer to measure the titanium isotopes in supernova SiC grains, scientists have been able to test theoretical calculations about the origins of the solar system.

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Pupil Size Couples to Cortical States to Protect Deep Sleep Stability
News

Researchers have found that mice pupil size fluctuates during sleep. They also show that pupil size is a reliable indicator of sleep states.

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Toothpaste Ingredient Could Help Fight Drug-Resistant Malaria
News

An ingredient commonly found in toothpaste could be employed as an anti-malarial drug against strains of malaria parasite that have grown resistant to one of the currently-used drugs.

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