Navigating Data Management Challenges in Every Phase of the Drug Discovery Life Cycle

Webinar

In this webinar, we’ll introduce you to laboratory information management systems (LIMS) and demonstrate how this software can help you achieve regulatory compliant, quality data management throughout your product’s lifecycle.

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Contrasting LBAs and LC-MS for Peptide and Protein Bioanalysis

Video

Kelly Doering discusses ligand binding assays (LBAs) and compares the advantages and limitations of this technology to LC-MS.

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Advances in Fragment-Based Drug Discovery

Article

Over the past decade, fragment-based drug discovery has garnered increasing interest among drug discovery experts and has established itself as a key approach within the field – acting as an alternative starting point for the discovery of high-quality lead candidates. This article discusses the evolution of FBDD, highlights key drug discoveries, and explores the advantages and challenges of harnessing this approach

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First-in-Human Trial Evaluating Ebola Treatment Begins

First-in-Human Trial Evaluating Ebola Treatment Begins

News

A first-in-human trial evaluating an experimental treatment for Ebola virus disease has begun. The Phase 1 clinical trial is examining the safety and tolerability of a single monoclonal antibody called mAb114

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Rapamycin Lotion Reduces Facial Tumors Caused by Tuberous Sclerosis
News

Addressing a critical issue for people with a genetic disorder called tuberous sclerosis complex (TSC), doctors reported that a skin cream containing rapamycin significantly reduced the disfiguring facial tumors affecting more than 90 percent of people with the condition.

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Protein Acts as Brake on Learning and Memory
News

Researchers have discovered a new way that the protein RGS14 functions as a molecular brake on learning and memory

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Myelin Encourages Neuronal Growth Following Spinal Cord Injury
News

Scientitsts report that adult rat myelin actually stimulated axonal outgrowth in rat neural precursor cells (NPCs) and human induced pluripotent (iPSC)-derived neural stem cells (NSCs).

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Exploiting the Tumor Microenvironment for Cancer Therapeutics

Exploiting the Tumor Microenvironment for Cancer Therapeutics

Article

It’s more than a century since Paget first proposed the ‘soil and seed’ hypothesis in cancer, providing evidence that the environment surrounding a tumor is as important as the tumor itself. Research in this area has gathered momentum and it’s now the focus of intense research efforts.

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A Hangover Pill? Tests on drunk mice show promise
Article

Scientists create capsules filled with natural enzymes usually found in liver cells to help the body process the alcohol faster.

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Will Microfluidic Cell Culture Fulfill its Long-awaited Potential?
Article

The first paper ever published on microfluidic cell culture is 19 years old. Microfluidic cell culture has now outgrown its infancy and is about to survive its teenage years. It has matured considerably but still needs to transition from academia into clinics and industry. Will it come of age?

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The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
Article

Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could result in more successful telomerase-related clinical therapeutics.

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