Advances in Fragment-Based Drug Discovery

Article

Over the past decade, fragment-based drug discovery has garnered increasing interest among drug discovery experts and has established itself as a key approach within the field – acting as an alternative starting point for the discovery of high-quality lead candidates. This article discusses the evolution of FBDD, highlights key drug discoveries, and explores the advantages and challenges of harnessing this approach

Read more

Contrasting LBAs and LC-MS for Peptide and Protein Bioanalysis

Video

Kelly Doering discusses ligand binding assays (LBAs) and compares the advantages and limitations of this technology to LC-MS.

Watch Now

Navigating Data Management Challenges in Every Phase of the Drug Discovery Life Cycle

Webinar

In this webinar, we’ll introduce you to laboratory information management systems (LIMS) and demonstrate how this software can help you achieve regulatory compliant, quality data management throughout your product’s lifecycle.

Read more
Tiny Particles Carry Tumor Shrinking Drugs into the Brain

Tiny Particles Carry Tumor Shrinking Drugs into the Brain

News

MIT researchers have now devised a new drug-delivering nanoparticle that could offer a better way to treat glioblastoma. The particles, which carry two different drugs, are designed so that they can easily cross the blood-brain barrier and bind directly to tumor cells.

Read more
 
Antitumor Immune Function in Liver Controlled by Gut Microbiome
News

Scientists have found a connection between bacteria in the gut and antitumor immune responses in the liver. The study showed that bacteria found in the gut of mice affect the liver’s antitumor immune function. The findings have implications for understanding the mechanisms that lead to liver cancer and for therapeutic approaches to treat them.

Read more

You Are What Your Mother Eats
News

While many factors, such as the age of the mother, overall health and genetics ultimately play a role, the correlation between a mother’s nutrition habits and metabolism has been proved to directly impact the growth of her child. And researchers believe they may be one step closer to knowing why.

Read more

Pigs as Models for Zika Virus Research
News

Zika virus is pathogenic to humans and nonhuman primates but does not naturally affect other species, complicating studies on pathogenesis and the evaluation of vaccines and antiviral therapies. Due to the similarities in physiology, anatomy and the immune system between pigs and humans it was evaluated if pigs can be used as human surrogates in Zika virus research.

Read more

 
 
 
 
Exploiting the Tumor Microenvironment for Cancer Therapeutics

Exploiting the Tumor Microenvironment for Cancer Therapeutics

Article

It’s more than a century since Paget first proposed the ‘soil and seed’ hypothesis in cancer, providing evidence that the environment surrounding a tumor is as important as the tumor itself. Research in this area has gathered momentum and it’s now the focus of intense research efforts.

Read more
 
Novel Collagen Membrane Improves Colon-on-a-Chip Functionality
Article

A microfluidic model of the colon has been built using natural tissue base matrix, which closely mimics the structure and function of the colon.

Read more

A Hangover Pill? Tests on drunk mice show promise
Article

Scientists create capsules filled with natural enzymes usually found in liver cells to help the body process the alcohol faster.

Read more

Will Microfluidic Cell Culture Fulfill its Long-awaited Potential?
Article

The first paper ever published on microfluidic cell culture is 19 years old. Microfluidic cell culture has now outgrown its infancy and is about to survive its teenage years. It has matured considerably but still needs to transition from academia into clinics and industry. Will it come of age?

Read more

 
 
 
 

We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy