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Drug Discovery

Drug Discovery

Successful BLI

Good Data. Rich Insights. More Discoveries.

Label-free biosensor technologies have emerged as a promising approach to identify high-value hits with a strong likelihood of success as a therapeutic. Unlike traditional approaches of drug discovery, they are fast, sensitive, and come with improved success rates towards high-value drug candidates.

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Septic Shock and Metastases: Finding the Culprits

A new molecule, based on the anti-diabetes drug metformin, can bind copper, found to be important in acute inflammation, sepsis and cancer dissemination, and thus holds great promise for new therapy.

Build Your Own Panel of Up to 21 Human Protein Biomarkers From a Pre-Validated Library of ∼ 200 Assays Covering Major Disease Areas content piece image

Build Your Own Panel of Up to 21 Human Protein Biomarkers From a Pre-Validated Library of ∼ 200 Assays Covering Major Disease Areas

Mix and match up to 21 protein assays with 99% combinability. Each and every assay is transparently validated to the highest standards and you can be fully confident that whatever combination of assays you select will work together and deliver high quality data with excellent specificity, sensitivity, and dynamic range

Design Hub

Chemaxon’s Design Hub

Design Hub is a drug design software that connects scientific rationale, project data and computational resources. The application takes data driven drug design to a whole new level while keeping your costs low.

Design Hub

Chemaxon’s Design Hub

Design Hub is a drug design software that connects scientific rationale, project data and computational resources. The application takes data driven drug design to a whole new level while keeping your costs low.

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Revolutionising in vitro Disease Models with iPSC Reprogramming Technology

In this Teach Me in 10, we are joined by Dr. Will Bernard to get a primer on the latest innovations in in vitro human cell technology.

A pulse line.

The Pulse: Psychedelic News From Technology Networks Issue 4

Hello and welcome to the Pulse, the monthly psychedelics industry roundup from Technology Networks and Analytical Cannabis. Here, we’ll highlight some of the most significant psychedelic industry news from the past month, including important announcements, pre-clinical work and the latest from groundbreaking psychedelic clinical trials.

Personalized mRNA Vaccine Could Be Used To Treat Pancreatic Cancer

An research team have been developing a personalized mRNA cancer-treatment vaccine approach. It is designed to help immune cells recognize specific neoantigens on patients’ pancreatic cancer cells.

Insomnia Medication Could Help Those Who Act Out Their Dreams While Sleeping

Mount Sinai researchers have published what they say is the first study to identify a new form of treatment for rapid eye movement (REM) sleep behavior disorder.

Meet Chinmo, the "Youth Gene"

Researchers have recently revealed that the gene Chinmo is resoposible for establishing the juvenile stage in insects, and may play a key role in metamorphosis.

First Oral Drug To Treat Moderate-to-Severe Crohn’s Disease Approved

Data from a Mount Sinai-led phase 3 trial published today in The New England Journal of Medicine show that upadacitinib, a breakthrough, once-daily oral medication, helps patients achieve and maintain clinical and endoscopic remission.

Floating cancer cells.

Protein Hyperactivation Could Kill Cancer Cells and Bacteria

Technology Networks had the pleasure of speaking with Walid A. Houry, professor of biochemistry at the University of Toronto, to find out about the discovery of compounds that can induce protease hyperactivation to kill cancer cells.

Improving Image Integrity in Scientific Papers

This article sheds light on the issue of image integrity in academic publishing and gives advice on how to reduce the risk.

Improving Time-to-Value for GxP Computer Systems

Jim Brooks shares top tips to overcome the biggest validation challenges and best practices for building and implementing a digital process data strategy to lead to smarter and faster validation.

The Pulse: Psychedelic News From Technology Networks Issue 3

Hello and welcome to the Pulse, the monthly psychedelics industry roundup from Technology Networks and Analytical Cannabis. Here, we’ll highlight some of the most significant psychedelic industry news from the past month, including important announcements, pre-clinical work and the latest from groundbreaking psychedelic clinical trials.

Silencing the Storm: Could Psychedelics Change How We Treat Migraine and Cluster Headache?

Emerging clinical trial data suggest that psychedelic compounds could benefit both millions of migraineurs and thousands of cluster headache sufferers who find limited benefit from even gold-standard treatments.

Tackling Cardiotoxicity During Drug Development content piece image

Tackling Cardiotoxicity During Drug Development

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Ultraviolet-Visible Spectroscopy

What Stops Pharma Labs Reaching Their Full Potential? content piece image

What Stops Pharma Labs Reaching Their Full Potential?

A half greyscale, half colour image of pills.

Is MDMA the Solution to PTSD?

Scientist Analysing

Reducing the Challenges Facing Pharmaceutical QC Analysts

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Weekly Science News Roundup

Data Integrity Risks

How To Reduce Data Integrity Risk

The aim of this guide is to provide practical advice on how to reduce data integrity risk and ensure GxP compliance. Learn from those in the industry who have failed to comply with data integrity regulations and who have been on the receiving end of an FDA inspection.

How To Detect and Avoid Cell Culture Contamination

In this guide, we take a look at how cell culture contamination can be avoided and some of the key ways it can be detected.

Reveal More With Accurate and Scalable Long-Read Sequencing

Long-read sequencing enables the accurate identification and characterization of complex genomic features. It outperforms its short-read alternatives in de novo assembly, mapping, and variant calling applications.

Revolutionary Binding Kinetics Analysis

Conventional bioassays often require labeled detection reagents to provide a measurable readout. However, modifications to molecular structure and/or function can skew results, and non-specific binding of the labels themselves can lead to an unwanted background signal.

A Guide to RNA-Seq

Download this guide to learn more about what RNA-Seq is and the information it provides, advantages of RNA-Seq, the types of RNA-Seq available and what to consider when designing your experiment.

Webinars & Online Events

3D RNA Imaging of Mouse Whole Brain at Single-Cell Resolution content piece image

3D RNA Imaging of Mouse Whole Brain at Single-Cell Resolution

Miltenyi Biotec

Uncovering Novel Psychoactive Substance Biomarkers Using Diagnostic Fragment Screening content piece image

Uncovering Novel Psychoactive Substance Biomarkers Using Diagnostic Fragment Screening

SCIEX

Exploring Tumor Innervation With Tissue Clearing and 3D Imaging content piece image

Exploring Tumor Innervation With Tissue Clearing and 3D Imaging

Miltenyi Biotec

Close up of a protein structure.

Recent Applications of Proteomics

High-Throughput Screening in Drug Discovery

High-Throughput Technologies in Biomedical Research

Five Intelligent Ways To Accelerate Cell Line Development

Ten Guidelines for Adopting Ontologies To Create FAIRer Scientific Data

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