Positive Allosteric Modulator Improves Neurodegenerative Outcomes

News

Global collaboration shows positive allosteric modulation of M1 Muscarinic receptors slows prion neurodegeneration and restores memory loss.

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Mitochondrial Genetic Switch Important For Parkinson's Disease

News

University of Leicester researchers have identified a genetic switch in the energy powerhouses of cells that could be a key target in the treatment of Parkinson's Disease.

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Seven days in science - 24 Feb 2017

Quiz

Test your knowledge of what's been happening in the scientific world over the past seven days.

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Leaf-Inspired Photomicroreactor Could Power A Step Change In The Chemical Industry

Article

We talk to Dr. Tim Noel about work and inspiration behind his group's latest design, a photomicroreactor.

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What Rings Do Medicinal Chemists Use, And Why?

Poster

Investigation into the most common ring system and substitution patterns in the recent medicinal chemistry literature, as derived from the ChEMBL database.

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Deciding When Not To Act On Instinct

Deciding When Not To Act On Instinct

News

Scientists uncover neural connection that can prevent us acting on instinct.

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Metrion Biosciences and Assay.Works Partner to Enhance Ion Channel Drug Discovery
News

As a result of the collaboration, Metrion now is now able to offer its clients access to High Throughput Screening (HTS) and Assay.Works assay validation technologies, including 384-well format screening and compound handling facilities.

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Breaking Through Immune Tolerance
News

A novel DNA cancer vaccine has shown promise by stimulating a therapeutic anti-tumor response against leukemia in mice.

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DNA Replication Depends on High Speed Electron Transport
News

Researchers have discovered that a key protein required for replicating DNA depends on electrons traveling through DNA.

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