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Latest App Notes & Case Studies

Liver Fibrosis
App Note / Case Study

A Novel Approach for Non-Invasive Liver Research

This case study utilizes non-invasive ultrasound imaging to visualize and quantify liver echogenicity and stiffness, providing critical insights into both disease progression and the efficacy of therapeutic interventions in mouse models.
engineered stable mAbs
App Note / Case Study

Biologics Developability: Optimization of Engineered mAbs With Multi-Parameter Stability Characterization

The biologic drug development process is expensive and often leads to time and money lost on candidates that never reach the clinic. Improved developability profiles enable researchers in the early discovery stages to select candidates that have a great chance at clinical success.
Neuro Research
App Note / Case Study

Speeding Up Neuroscience Research

Delve into this case study to explore how a research lab at King’s College London used hiPSC-derived neurons to shed light on synaptic biology and potential treatments for psychiatric conditions.
Neuro Program
App Note / Case Study

Precision Reprogrammed iPSC Models for High-Throughput Drug Discovery

This app note delves into the role of TDP-43 protein aggregates in the disease's progression. Charles River Laboratories and bit.bio present a breakthrough in ALS research with genetically matched ioGlutamatergic Neurons, providing a crucial in vitro model.
AKTA System
App Note / Case Study

Single-Use Technology Designed for Small Batches in Gene Therapy Manufacturing

But how do you purify small volumes for preclinical and clinical studies without losing too much to processing or leaving capacity unused?
High Throughput Bulk RNA Barcoding and Sequencing
App Note / Case Study

High-Throughput Bulk RNA Barcoding and Sequencing

This app note highlights a convenient, efficient and reliable workflow for massively multiplexed RNA-seq experiments.
Vaccine Vials
App Note / Case Study

Viral Clearance in a Downstream AAV Process

This application note shows how chromatographic modes of separation can achieve the necessary levels of virus removal while preserving the integrity of the AAV product.
App Note / Case Study

Streamlined Detection and Characterization of Mitochondrial Toxicants

This app note highlights an assay that enables streamlined, sensitive detection and characterization of mitochondrial toxicants.
Evaluating Bacterial Biofilms With Confocal Imaging
App Note / Case Study

Evaluating Bacterial Biofilms With Confocal Imaging

Discover a single confocal imaging reader able to replace up to five individual devices and perform a variety of analysis outcomes common in biofilm workflows, including biomass screening, characterizing growth architecture and antibiotic susceptibility testing.
Glycagon
App Note / Case Study

Achieve Sensitive Quantitation of GLP Analogs in Biological Matrices

Glucagon-like peptide-1 (GLP-1) analogs regulate systemic homeostasis, making them effective in the treatment of type 2 diabetes. However, their low bioavailability limits their detection and quantitation in biological matrices, causing challenges in drug development.
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