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Latest App Notes & Case Studies

Brochure on E. coli fermentation scale-up from 200L stainless steel to 1000L single-use fermenter
App Note / Case Study

Successful Scale-Up for High-Density Microbial Processes

This application note highlights the successful 5-fold scale-up of a high-cell density E. coli process from an established 200 L stainless steel fermenter to a 1000 L single-use system.
Close up of a womens hand in a glove with a test tube.
App Note / Case Study

Optimizing Metabolite Identification With Electron-Activated Dissociation

This app note highlights the advantages of electron-activated dissociation (EAD) in identifying oxidative metabolites of the molecular glue, mezigdomide.
Women using a asthma inhaler
App Note / Case Study

Ultra-Sensitive Quantification of Fluticasone Propionate

This application note highlights a LC-MS/MS method that leverages advanced sample preparation and next-generation detection technology to achieve high sensitivity and accuracy while minimizing sample volume requirements.
Open scientific brochure on kinase inhibitors, featuring a 3D molecular structure on the cover and a pathway diagram inside
App Note / Case Study

Next-Generation Kinase Inhibitors: Overcoming Resistance and Enhancing Clinical Outcomes

This content introduces the physiological and pathological importance of protein kinases, kinase inhibitors approved for clinical use, and next-generation kinase inhibitors.
3D-rendered illustration of stem cells with glowing orange nuclei suspended in a fluid environment
App Note / Case Study

Transform MSC Research With Real-Time, Non-Invasive Differentiation Monitoring

This application note demonstrates how combining live-cell analysis with high-throughput screening cytometry enables continuous, non-invasive monitoring of MSC differentiation, offering unprecedented insights into cellular dynamics while preserving
Cover for application note featuring guidelines on contamination management and laboratory balance maintenance
App Note / Case Study

How To Manage Contamination of Your Analytical Balance

This application note explores how a new generation of modern analytical balances benefit from hardware and software features that make cleaning processes easier and safer.
Colorful 3D molecular models of antibodies highlighting protein structure and immune system functionality
App Note / Case Study

Unraveling Protein Complex Dynamics

Discover how cutting-edge methodologies capture transient interactions with precision, providing a deeper understanding of complex binding dependencies.
Scientist using a pipette for antibody analysis in a laboratory, with samples in a multi-well plate and petri dish.
App Note / Case Study

Faster, Reliable Cell Line Development Solutions

This case study highlights a novel platform that enabled a research team to identify, isolate and expand rare NIH-3T3 clones expressing HER2 and EBFP2, achieving results in weeks rather than months.
Microscopic view showing HUVEC fibroblast cells with green fluorescence and purple outlines
App Note / Case Study

Discover a High-Throughput, Real-Time Angiogenic Tube Formation Assay

This application note highlights a high-throughput angiogenic tube formation assay using a co-culture of HUVECs and fibroblasts, enabling efficient and accurate drug discovery screening.
3D visualization of protein interactions on a cell surface, illustrating mechanisms in assay development
App Note / Case Study

Gain Deeper Insights in Proteomics Research

This application note showcases how this robust, highly multiplexed platform supports novel biomarker discovery in drug development and aids in developing diagnostics for a wide range of critical diseases.
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