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Latest Application Notes
Revolutionizing Drug Discovery in Hematological Oncology
Application Note

Revolutionizing Drug Discovery in Hematological Oncology

The approach to treating hematological malignancies is rapidly evolving as we discover the underlying mechanisms of disease and identify new immune pathways within the patient’s body to harness.
Reliable and High-Throughput Cell Viability Assays
Application Note

Reliable and High-Throughput Cell Viability Assays

The determination of cell viability in any cell culture is a crucial analytical measurement for any study. One of the most common ways to measure cell viability is via the determination of the cell membrane’s integrity.
Transforming Drug Discovery Through Precision Research
Application Note

Transforming Drug Discovery Through Precision Research

The high resolution and scale that single cell analysis provides is revolutionizing drug discovery and development by introducing comparative, longitudinal and causal information that transforms our ability to understand biology and disease.
Imaging Organoids With Light-Sheet Fluorescence Microscopy
Application Note

Imaging Organoids With Light-Sheet Fluorescence Microscopy

Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.
Accurate Quantification of Interferon Gamma Across Immunoassay Platforms
Application Note

Accurate Quantification of Interferon Gamma Across Immunoassay Platforms

Download this app note to discover immunoassay platforms that are consistent for your cell therapy and immunology development needs.
Organoids for Disease Modeling and <i>In Vitro</i> Drug Screening
Application Note

Organoids for Disease Modeling and In Vitro Drug Screening

While the complexity of organoids remains challenging, technological advances are enabling organoids to be developed and monitored in an automated fashion, so that they can be exploited in high-throughput drug screening assays.
3D Co-Culture Spheroids With Human Liver Cells
Application Note

3D Co-Culture Spheroids With Human Liver Cells

With the advances in 3D culture, liver spheroids made from primary human hepatocytes have been demonstrated to be a useful novel tool for in vitro hepatotoxicity studies.
Applications Using Human Liver Spheroids
Application Note

Applications Using Human Liver Spheroids

Recently, the advantages of PHH liver spheroids use in liver toxicity tests over the traditional 2D monolayer culture of PHHs has been demonstrated by many scientists.
Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis
Application Note

Enhancing the Therapeutic Properties of a Cancer-Targeting Affibody by Soft Mutagenesis

Affibodies are synthetic antigen-binding proteins. They offer many advantages over monoclonal antibodies, including smaller sizes, enhanced thermal stability and rapid refolding capability. These advantages make affibodies an attractive platform for the development of therapeutics, diagnostics and bioimaging technology.
Tiling Across Viral Genomes to Investigate Immune Escape
Application Note

Tiling Across Viral Genomes to Investigate Immune Escape

Viruses exploit high-dimensional RNA structures to facilitate viral replication and impede host restriction. Here, a novel next-generation sequencing (NGS)-based screening workflow, called Fate-seq, was used to define and characterize high-dimensional RNA structures.
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