Latest App Notes & Case Studies
App Note / Case Study
Automated Protein Sample Preparation in Regulated Environments
Download this application focus to learn more about the benefits of automated sample preparation for drug development.
App Note / Case Study
Detection and Characterization of Mitochondrial Toxicity
A Customized XF Workflow for Detection and Characterization of Mitochondrial Toxicity
Many different classes of drugs can cause drug-induced mitochondrial toxicity, which may result in brain, cardiac, liver, muscle and/or kidney injury.
Many different classes of drugs can cause drug-induced mitochondrial toxicity, which may result in brain, cardiac, liver, muscle and/or kidney injury.
App Note / Case Study
Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity
Surface plasmon resonance (SPR) is a core technology used in many pharma and biotechnology settings for this purpose, however traditional initial SPR screening of weak affinity compounds using a single fixed concentration injection can present numerous challenges.
App Note / Case Study
CRISPR Engineered Cells Enable Variant Disease Modeling
Comprehensive disease modeling can be challenging for many labs due to variations in reagents, cell culture conditions, technical inconsistencies across protocols and experiments and bandwidth limitations.
App Note / Case Study
Analysis of Lipid Nanoparticle Composition
In recent years, interest in lipid nanoparticle (LNP) research has increased due to promising opportunities for RNA-based therapy and gene-editing technology, and LNPs are showing promise as nucleic acid delivery vehicles in the pharmaceutical industry.
App Note / Case Study
Cell Painting for Phenotypic Screening
Cell painting is a powerful phenotypic screening method used to gain a deeper understanding of the effects of chemical and genetic perturbagens on cells.
App Note / Case Study
From Mammalian Cell Cultures to Pure Proteins: Reduce Your Cell Harvest Time
For therapeutic applications, it is important that protein production from mammalian cell lines is efficient and pure.
App Note / Case Study
Identification of Cardiac Liability in Drug Discovery
Download this app note to discover how patch-clamp can be used as part of an integrated risk assessment in first-in-human studies as well as later stages of clinical development.
App Note / Case Study
Feel the Need, the Need for Speed: Advances in RapidFire-MS Analyses for Faster, Larger Runs with Less Sample Preparation
Download this free application focus to learn more about how Agilent's latest RapidFire 400 mass spectrometry system.
App Note / Case Study
Are You Compliant When it Comes to Pipetting?
During pharmaceutical development and manufacturing, there is always the question: are you following methods for current good laboratory practice or current good manufacturing practice?
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