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Latest App Notes & Case Studies

Automated Protein Sample Preparation in Regulated Environments content piece image
App Note / Case Study

Automated Protein Sample Preparation in Regulated Environments

Download this application focus to learn more about the benefits of automated sample preparation for drug development.
Detection and Characterization of Mitochondrial Toxicity content piece image
App Note / Case Study

Detection and Characterization of Mitochondrial Toxicity

A Customized XF Workflow for Detection and Characterization of Mitochondrial Toxicity

Many different classes of drugs can cause drug-induced mitochondrial toxicity, which may result in brain, cardiac, liver, muscle and/or kidney injury.
Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity content piece image
App Note / Case Study

Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity

Surface plasmon resonance (SPR) is a core technology used in many pharma and biotechnology settings for this purpose, however traditional initial SPR screening of weak affinity compounds using a single fixed concentration injection can present numerous challenges.
CRISPR Engineered Cells Enable Variant Disease Modeling content piece image
App Note / Case Study

CRISPR Engineered Cells Enable Variant Disease Modeling

Comprehensive disease modeling can be challenging for many labs due to variations in reagents, cell culture conditions, technical inconsistencies across protocols and experiments and bandwidth limitations.
Analysis of Lipid Nanoparticle Composition content piece image
App Note / Case Study

Analysis of Lipid Nanoparticle Composition

In recent years, interest in lipid nanoparticle (LNP) research has increased due to promising opportunities for RNA-based therapy and gene-editing technology, and LNPs are showing promise as nucleic acid delivery vehicles in the pharmaceutical industry.
Cell Painting for Phenotypic Screening content piece image
App Note / Case Study

Cell Painting for Phenotypic Screening

Cell painting is a powerful phenotypic screening method used to gain a deeper understanding of the effects of chemical and genetic perturbagens on cells.
From Mammalian Cell Cultures to Pure Proteins: Reduce Your Cell Harvest Time content piece image
App Note / Case Study

From Mammalian Cell Cultures to Pure Proteins: Reduce Your Cell Harvest Time

For therapeutic applications, it is important that protein production from mammalian cell lines is efficient and pure.
Identification of Cardiac Liability in Drug Discovery content piece image
App Note / Case Study

Identification of Cardiac Liability in Drug Discovery

Download this app note to discover how patch-clamp can be used as part of an integrated risk assessment in first-in-human studies as well as later stages of clinical development.
Feel the Need, the Need for Speed: Advances in RapidFire-MS Analyses for Faster, Larger Runs with Less Sample Preparation content piece image
App Note / Case Study

Feel the Need, the Need for Speed: Advances in RapidFire-MS Analyses for Faster, Larger Runs with Less Sample Preparation

Download this free application focus to learn more about how Agilent's latest RapidFire 400 mass spectrometry system.
Are You Compliant When it Comes to Pipetting? content piece image
App Note / Case Study

Are You Compliant When it Comes to Pipetting?

During pharmaceutical development and manufacturing, there is always the question: are you following methods for current good laboratory practice or current good manufacturing practice?
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