Latest App Notes & Case Studies

After the discovery of unacceptable levels of nitrosamine contaminations in certain drug products, regulatory agencies around the world have mandated stringent guidelines and analytical testing of all pharmaceuticals, especially chemically synthesized ones.

With an ever-increasing consumption of pharmaceutical products by the world population, there are considerable concerns about the unknowns and impurities which are ingested along with these medicinal drugs

Pharmaceutical analysis in drug development mainly focuses on methods to identify and quantify potential new drug candidates. It is imperative that effective, robust methods are used to maintain the safety of the product.

The structural and chemical complexity of biologics, combined with the intricacy of cell-based manufacturing, imposes a huge analytical burden to correctly characterize and quantify both processes (upstream) and products (downstream).

Download this app note to discover a system that can be used for product formulation, diafiltration solutions as well as extraction, rinsing and sanitization steps.

Download this app note to discover a gut MPS that has physiologically relevant morphology, reduced barrier integrity and mucus expression. It can be used to predict drug permeability across an intestinal barrier.

Food fraud is a rapidly growing and evolving business, therefore several analytical methods have recently been developed to address the concern regarding food adulteration.

Antibody–drug conjugates (ADCs) are monoclonal antibodies to which a cytotoxic small molecule drug is chemically linked. The structures of ADCs are more complex than their corresponding antibodies.

Antibodies are subject to instability issues due to chemical and physical instabilities and these effects can change the pharmacokinetics of the antibody. For this reason, produced antibodies must be thoroughly tested before they can be applied for treatment of patients.

Download this info kit to discover solutions that can analyze compounds with positive or negative polarity and provide easy-to-use kits for a variety of protein workflows.