Latest Application Notes
Solutions for Pharmaceutical Impurities
With an ever-increasing consumption of pharmaceutical products by the world population, there are considerable concerns about the unknowns and impurities which are ingested along with these medicinal drugs
Solutions for Pharmaceutical Analysis
Pharmaceutical analysis in drug development mainly focuses on methods to identify and quantify potential new drug candidates. It is imperative that effective, robust methods are used to maintain the safety of the product.
Enabling Real-Time Release of Final Products in Manufacturing of Biologics
The structural and chemical complexity of biologics, combined with the intricacy of cell-based manufacturing, imposes a huge analytical burden to correctly characterize and quantify both processes (upstream) and products (downstream).
Preventing Cell Death
Download this app note to discover a system that can be used for product formulation, diafiltration solutions as well as extraction, rinsing and sanitization steps.
Predicting Drug Permeability With a Gut Microphysiological System
Download this app note to discover a gut MPS that has physiologically relevant morphology, reduced barrier integrity and mucus expression. It can be used to predict drug permeability across an intestinal barrier.
Black Pepper Authenticity Workflow
Food fraud is a rapidly growing and evolving business, therefore several analytical methods have recently been developed to address the concern regarding food adulteration.
Convenient and Reliable Analysis of Antibody–Drug Conjugates
Antibody–drug conjugates (ADCs) are monoclonal antibodies to which a cytotoxic small molecule drug is chemically linked. The structures of ADCs are more complex than their corresponding antibodies.
Preparation of Buffers and Solutions for Therapeutic Antibody Analysis
Antibodies are subject to instability issues due to chemical and physical instabilities and these effects can change the pharmacokinetics of the antibody. For this reason, produced antibodies must be thoroughly tested before they can be applied for treatment of patients.
CE-MS Solutions Enabling Next-Generation Therapeutics
Download this info kit to discover solutions that can analyze compounds with positive or negative polarity and provide easy-to-use kits for a variety of protein workflows.
A Validated Method for the Rapid Determination of Fifteen Nitrosamines
Nitrosamines are categorized as probable carcinogens by the ICH M7 (R1) guideline. Since June 2018, several drugs have been recalled due to the presence of these impurities, in particular the U.S.