Latest Application Notes
Target-Class Selectivity Profiling for Deubiquitinase (DUB) Inhibitors
Download this app note to discover a solution that provides accurate quantification with multiplexed stable isotope reagents, unprecedented coverage of cellular DUB enzymes and evidence that hits in a high-throughput biochemical screen are indeed selective for intended targets.
Microbubbles Offer a Versatile, Flexible Platform for Targeted Capture of Diverse Analytes
Download this app note to discover a solution that can be used with any biotinylated affinity molecule, enables floatation-based separation of diverse targets as well as provides workflows that are exceptionally gentle on delicate analytes.
Improve Your XL-MS Results
Proteins typically fold into well-defined tertiary structures and interact with other proteins to form homo- and hetero-oligomers to accomplish their physiological functions. These functions have implications on health and disease, but are also relevant for biotechnology applications.
Revolutionizing Drug Discovery in Hematological Oncology
The approach to treating hematological malignancies is rapidly evolving as we discover the underlying mechanisms of disease and identify new immune pathways within the patient’s body to harness.
Reliable and High-Throughput Cell Viability Assays
The determination of cell viability in any cell culture is a crucial analytical measurement for any study. One of the most common ways to measure cell viability is via the determination of the cell membrane’s integrity.
Transforming Drug Discovery Through Precision Research
The high resolution and scale that single cell analysis provides is revolutionizing drug discovery and development by introducing comparative, longitudinal and causal information that transforms our ability to understand biology and disease.
Imaging Organoids With Light-Sheet Fluorescence Microscopy
Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.
Accurate Quantification of Interferon Gamma Across Immunoassay Platforms
Download this app note to discover immunoassay platforms that are consistent for your cell therapy and immunology development needs.
Organoids for Disease Modeling and In Vitro Drug Screening
While the complexity of organoids remains challenging, technological advances are enabling organoids to be developed and monitored in an automated fashion, so that they can be exploited in high-throughput drug screening assays.
3D Co-Culture Spheroids With Human Liver Cells
With the advances in 3D culture, liver spheroids made from primary human hepatocytes have been demonstrated to be a useful novel tool for in vitro hepatotoxicity studies.