Latest Application Notes
Your Guide to mAb Variants
Antibody-based derivatives have received increased attention as therapeutics in biopharmaceutical development because of their unique capacity to engage multiple molecular targets, engage immune effector cells or even penetrate tissues previously inaccessible to conventional mAbs.
Analysis of Genotoxic Nitrosamines in Losartan
Download this app note to discover a system that demonstrates good chromatographic separation of nitrosamine compounds and provides enhanced sensitivity.
Greater Precision for Transformative Drug Discovery
Target identification and characterization are key challenges in drug discovery and begin with identifying the function of a possible therapeutic target and its role in the disease.
Development of an AlphaLISA Protein-Protein Interaction Assay To Screen for Re-Purposed Drugs as Targeted Disruptors
The threat of global pandemics emphasises the quick identification of the cause of an emerging disease and its route of infection. Once these characteristics are defined, drug repurposing offers to identify previously approved drugs that might be applicable and quickly approvable for the treatment of the new disease.
Monitoring T-Cell Exhaustion and Effects of Immunotherapy
The efficient monitoring of T-cell surface markers, cytokines and expression patterns is critical to the study of further immunotherapies. Download this app note to discover how cell analyzers can help.
MTT Cell Proliferation, Viability and Cytotoxicity Assay
The MTT cell proliferation assay is a commonly used colorimetric assay for assessing cellular metabolic activity. Download this app note to discover how using a pipetting robot with this assay can reduce time and costs and allow processing of different plate formats.
Nucleic Acid Analysis for Sample Quality Assessment
Download this application compendium to discover analyzer systems that eliminate common QC bottlenecks, improve lab efficiency and deliver reliable and accurate nucleic acid sample assessment.
Rapid MS/MS Analysis With Acoustic Ejection Mass Spectrometry
Download this app note to discover a system that provides high-speed and reproducible quantification, has broad compound coverage and is purpose built for incorporation into high-throughput screening workflows.
Maintaining the Health and Viability of Cells
Cell culture can be a challenging process because cells are influenced by many factors including how they are physically handled and the labware used to seed and feed cultures.
Improve Recovery of Critical Protein Samples
Protein loss during sample preparation can be an obstacle to reliable product quantitation in all biopharmaceutical settings. Samples are often prepared from feedstocks containing insoluble particles and therefore require a solid-liquid separation before analysis to protect analytical instruments.