Latest App Notes & Case Studies
App Note / Case Study
The ELISAONE ™ Assay Performed on the POLARstar Omega from BMG LABTECH
ELISAONE ™ technology has been developed by TGR BioSciences to provide a means of running high performance sandwich immunoassays in a user-friendly 96-well format.
App Note / Case Study
An AlphaScreen® SureFire® Phospho-ERK1/2 Assay Performed on BMG LABTECH’s POLARstar Omega
G-protein coupled receptors (GPCRs) are a large family of receptors which have a broad involvement in cellular responses affecting many important body functions both in health and disease.
App Note / Case Study
A Fast and Simple Method For Measuring P-Glycoprotein (Pgp) Inhibition
Pgp expression has been linked to the effl ux of chemotherapeutic
drugs in human cancers leading to multidrug resistance. Pgp
activity can also result in low oral absorption and poor brain
penetration. Interaction of drugs with the Pgp may also cause
an increase in toxicity of co-administered compounds.
drugs in human cancers leading to multidrug resistance. Pgp
activity can also result in low oral absorption and poor brain
penetration. Interaction of drugs with the Pgp may also cause
an increase in toxicity of co-administered compounds.
App Note / Case Study
Quantitative Determination of Total Bile Acids with a Thermo Scientific Varioskan Flash Multimode Reader Using a Kinetic Enzyme Cycling Assay
Serum total bile acids (TBA) level is a long-established and accepted indicator of liver diseases. This application note presents a simple photometric measurement of serum TBA.
App Note / Case Study
LanthaScreen TR-FRET Assay Performance with Thermo Scientific Varioskan Flash Spectral Scanning Multimode Reader
LanthaScreen technology uses time-resolved fluorescence resonance energy transfer (TR-FRET) to study multiple target classes including protein kinases, nuclear hormone receptors, as well as proteases and ubiquitinated proteins.
App Note / Case Study
Optimization of Instrument Settings and Measurement Parameters for Kinetic Fluorometric and Luminometric Assays
When fluorometric and luminometric assays are performed in microplate format, a high number of samples can be analyzed at a time. The speed of the reaction kinetics of the assay determines the requirements for the detection instrument and measurement parameters for achieving the best possible performance of the assay.
App Note / Case Study
Pipetting performance of Thermo Scientific Finnpipette F2 in combination with Thermo Scientific Finntip Flex
The Finnpipette® F2 product family has been designed by taking into account the demands of today´s laboratory work and the require¬ments of the end users. It offers superior comfort, performance, reliability and repeatability in one of the lightest pipettes available.
App Note / Case Study
Turbidometric Growth Curve Measurements and Liquid Evaporation Studies with a Microplate Photometer
The turbidity of a liquid sample is traditionally measured either with a nephelometer or a photometer. The measure of turbidity (also called optical density, OD) refers to the scattering of light from the particles of the measured sample. When measuring turbidity of a bacterial culture, the amount of scattered light is directly proportional to the number of bacterial cells in the sample.
App Note / Case Study
High Sensitivity ELISA Assays for the Detection of Melamine Residuals in Milk
Melamine is an industrial chemical most commonly used as a fire retardant in dry powder extinguishers due to its release of nitrogen gas when burned or charred. Melamine has been used illegally by adding it to food products in order to increase the apparent protein content.
App Note / Case Study
Facilitating Biofilms Assays with Thermo Scientific Multidrop® Combi Dispenser
In recent years, the automation of cell (including bacteria)-based screening assays has consistently shown to provide reduced times and considerable labor saving, while maintaining or increasing assay quality during screening campaigns.
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