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3D Cell Panel Screens for Drug Discovery and Development

High throughput cell panel screens are a key drug development tool for identifying sensitive tumour types and genomic features governing response. Two-dimensional monolayer assay formats are the traditional mainstay for these screens, which have facilitated the development of many successful drugs. However, it is increasingly recognised that they do not accurately model key aspects of the three-dimensional (3D) tumour microenvironment.

Download this app note to discover 3D panel screens that:

  • Could improve predictions of clinical outcomes
  • Reduce the high failure rate of cancer drugs in clinical trials 
  • Enables screening across a panel of 200 cell lines