Latest Application Notes
Transfection of Primary Human Hepatocytes
Download this app note to learn more about novel cell culture systems and their benefits in comparison to conventional technologies.
Biological Characterization and Purification - From Discovery to Quality Control
Download this conpendium to understand more about the challenges associated with biopharmaceuticals, how analytical solutions are used to purify biologicals, and more.
Solutions for Viral Research Workflows
Download this app note to learn more about sample collection, analysis of antibodies and how these can be utilized to manufacture vaccines.
Advancing Development of Coronavirus Vaccines and Therapeutics
Download this application note to learn more about the techniques used for the development of therapeutics against COVID-19
Binding Kinetics: High Throughput Assay for Kinase Inhibitors
Download this app note to discover more about binding parameters and high-throughput assays in drug development.
Achieve Successful Immunoprecipitation With Dynabeads
Immunoprecipitation in its basic form is very simple, however protein–protein binding often involves transient and weak interactions. It is therefore paramount to use a method that offers rapid binding kinetics and low nonspecific binding.
Proteomic Interrogation of Primary Insulin-Secreting Pancreatic β-cells
Dr Jarrod Marto’s lab from the Dana-Farber Cancer Institute have developed a new approach to identify expression of low-level enzymes for the first time in primary insulinsecreting beta cells (β-cells). In their research, they found that these proteins are critical, functional components of key metabolic pathways which can support β-cell survival under inflammatory stress.
Two-Dimensional Isolation of Target Compounds From Complex Natural Products
To date, mostly offline 2D-LC is used for two-dimensional purification, which is time-consuming, difficult to automate, and can incur sample loss or contamination. Download this app note to discover how online 2D-LC can help you overcome these issues.
Annotation of Saponins in Chinese Medicines Using Structure-Based MS
Despite possessing numerous advantageous pharmacological properties, the comprehensive annotation of saponins remains challenging. Download this app note to discover how a structure-based mass spectrometry workflow can be used.
Safety, Sample Integrity and Throughput With Semi-Automated Sample Tube Decapping
Download this app note to discover how semi-automated sample tube decapping can ensure sample integrity whilst also helping to prevent injury.