Latest App Notes & Case Studies

Developed for performance in human serum and plasma, the SomaScan Assay v4.1 can measure approximately 7,000 unique human protein analytes in small volumes of biological samples.

This app note presents a robust workflow that combines automated sample preparation, hydrophilic interaction chromatography and triple quadrupole mass spectrometry that can be applied to plasma and mammalian cell samples.

Single-cell RNA sequencing produces a substantial amount of complex data that can be a burden if you don’t have time to become an expert in bioinformatics.

Antibody drug conjugates (ADCs) are biotherapeutics, composed of small molecule drugs conjugated to an antibody scaffold, that have very complex molecular structures.

Energy metabolism plays a central role in a wide variety of cellular and physiological processes. Therefore, a deep understanding of how disruption to energy metabolism impacts cells can help in therapeutic drug discovery and development.

Download this app note to discover a method of recombinant protein expression that enables correct protein folding and post translational modification, is suitable for high-density cell culture, and can produce both secreted and intracellular proteins of various species.

There is currently no effective cure or treatment to slow down or stop the progression of Huntington's disease (HD). One reason for this is the lack of accurate and easy-to-use HD models.

Proteolysis targeting chimera (PROTAC) degraders are used to treat drug-resistant targets via targeted protein degradation.

Rare cells play pivotal roles in disease initiation, maintenance and progression. Yet, identifying these cells remains a difficult task for low-plex technologies, as it is not always clear a priori which biomarkers distinguish rare phenotypes from the remaining population.

In drug screening, conventional high-throughput applications evaluate only a few measurements and have limited breadth to detect diverse phenotypic changes caused by compound exposure.