Latest App Notes & Case Studies
App Note / Case Study
Microscale Separation: A Chromatography System for Low Volume Size Exclusion Chromatography
The structural characterization of complex proteins gives researchers a glimpse into their in vivo mechanistic functions and complex chemistries. In the case of drug development, structural information of proteins involved in disease pathways is crucial for downstream rational design of novel therapeutics.
App Note / Case Study
Target-Class Selectivity Profiling for Deubiquitinase (DUB) Inhibitors
Download this app note to discover a solution that provides accurate quantification with multiplexed stable isotope reagents, unprecedented coverage of cellular DUB enzymes and evidence that hits in a high-throughput biochemical screen are indeed selective for intended targets.
App Note / Case Study
Microbubbles Offer a Versatile, Flexible Platform for Targeted Capture of Diverse Analytes
Download this app note to discover a solution that can be used with any biotinylated affinity molecule, enables floatation-based separation of diverse targets as well as provides workflows that are exceptionally gentle on delicate analytes.
App Note / Case Study
Improve Your XL-MS Results
Proteins typically fold into well-defined tertiary structures and interact with other proteins to form homo- and hetero-oligomers to accomplish their physiological functions. These functions have implications on health and disease, but are also relevant for biotechnology applications.
App Note / Case Study
Revolutionizing Drug Discovery in Hematological Oncology
The approach to treating hematological malignancies is rapidly evolving as we discover the underlying mechanisms of disease and identify new immune pathways within the patient’s body to harness.
App Note / Case Study
Reliable and High-Throughput Cell Viability Assays
The determination of cell viability in any cell culture is a crucial analytical measurement for any study. One of the most common ways to measure cell viability is via the determination of the cell membrane’s integrity.
App Note / Case Study
Transforming Drug Discovery Through Precision Research
The high resolution and scale that single cell analysis provides is revolutionizing drug discovery and development by introducing comparative, longitudinal and causal information that transforms our ability to understand biology and disease.
App Note / Case Study
Imaging Organoids With Light-Sheet Fluorescence Microscopy
Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.
App Note / Case Study
Accurate Quantification of Interferon Gamma Across Immunoassay Platforms
Download this app note to discover immunoassay platforms that are consistent for your cell therapy and immunology development needs.
App Note / Case Study
Organoids for Disease Modeling and In Vitro Drug Screening
While the complexity of organoids remains challenging, technological advances are enabling organoids to be developed and monitored in an automated fashion, so that they can be exploited in high-throughput drug screening assays.
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