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Identifying Metabolites With Confidence

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Understanding the effects of in vitro drug metabolism is a key aspect of drug discovery and development. However, researchers must be able to make confident decisions quickly and easily.

Electron-activated dissonance (EAD) is a novel orthogonal fragmentation technique that supports drug metabolism studies by providing more information-rich product ion spectra.  

This application note presents a new workflow for in vivo metabolism studies that incorporates EAD and enables researchers to develop confident structure-metabolic stability relationships for pharmaceutical drugs.

Download this application note to discover how you can:

  • Detect low-level metabolites with enhanced sensitivity
  • Achieve faster characterization and identification of metabolites 
  • Streamline data acquisition and processing workflows


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