Illuminating the Role of the Adaptive Immune Response in Neurodegeneration

The role of the adaptive immune system in neurodegenerative diseases, such as Alzheimer’s, is controversial. Although neuroinflammation is thought to drive the pathology of age-related neurodegenerative diseases, a comprehensive understanding requires additional insights, including clarity into which T cell clones are expanded in the disease state and the antigens to which they are responding.

Download this research snapshot to discover:

• How the immune repertoire changes in patients with age-related neurodegeneration

• How adaptive immune cells are involved in these neurodegenerative diseases

• An approach to studying key immune changes in neurodegeneration at single cell resolution