Nephelometric Monitoring Growth of Candida albicans Using BMG LABTECH’s NEPHELOstar
Application Note Mar 31, 2009
Laser nephelometry has been shown to be a reliable technique for the measurement of drug solubility in 96-well plate format. In this note the use of BMG LABTECH´s NEPHELOstar to investigate the effects of complexation on the drug antimycotic activity is described. Laser nephelometry can distinguish between the concentration at which the drug just goes into or just comes out of solution. This is presented in phase solubility studies. Furthermore nephelometry was used to monitor fungal growth.