Latest Articles

How We Tackle Antibiotic Resistance Now
Article

The fight against antibiotic resistance is real and is something we all have a responsibility in tackling. In fact, Antibiotic resistance kills an estimated 700,000 people each year and has fuelled the re-emergence of illnesses that had become a rarity in many parts of the world.

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Practical Guidance for the Confident Application of Differential Scanning Calorimetry
Article

In this article, we provide practical guidance for the application of differential scanning calorimetry (DSC), a core technique for studying the stability and higher order structure (HOS) of proteins. We explain how DSC works, and highlight good practice for ensuring optimal data quality. The interpretation and value of the resulting data is also discussed.

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Bioimaging Using Microscopes: Challenges, Benefits and the Future
Article

The imaging of biological samples, or bioimaging, plays a key role in current life science research, enabling scientists to analyze molecules, cells and tissues from a range of living systems.

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Advancing Drug Discovery Through Academic–Industry Collaboration
Article

Genestack recently announced that they were joining the Milner Therapeutics Institute. In light of the announcement, I spoke to Prof. Tony Kouzarides, Director of the Milner Therapeutics Institute and Dr. Misha Kapushesky, Founder and CEO of Genestack, to learn more.

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The MAPK Pathway as a Therapeutic Target in Cancer Research
Article

Following the rapid and striking success of vemurafenib, a MAPK targeting drug used to treat melanoma, interest in this critical cell signalling pathway has exploded.

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Protein Biotherapeutics: Mass Spectrometry Analysis
Article

Mass spectrometry has evolved as a prevailing technique for both the characterization of biotherapeutics and identification of protein variants and post-translational modifications.

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Targeted Drug Delivery Via Nanoparticles Could Help Repair Transplant Organs
Article

Scientists have designed targeted nanoparticles to aid the therapeutic delivery of drugs directly to organs. This new technique could increase the number of viable organs available for transplantation.

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NMR Spectroscopy: A Brief Guide
Article

Nuclear magnetic resonance spectroscopy is a non-destructive analytical technique that enables interrogation of the nature and structure of organic compounds. It is proving an invaluable tool in food provenance investigation and recent advances to improve analysis speed and sensitivity look set to continue this trend.

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Spectroscopic Techniques for Food Analysis to Combat Adulteration and Fraud
Article

Food fraud takes many forms, including adulteration, package tampering, outright counterfeiting of products or ingredients, mislabeling, intentional use of illegal or substandard ingredients, manufacturing shortcuts to lower production costs, and many others. Thanks to modern technology, detecting food fraud is mostly an analytical chemistry exercise, with choice of methodology depending on the quality attribute the food detective is looking for.

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The Importance of Aflatoxin Discrimination in Food Testing
Article

Aflatoxins have been an issue in food and feed since the 1970’s, but the first global effort to regulate them took place in 2003. Aflatoxin B1 is by far the most prevalent and potent sub-type. Accordingly, maximum levels for B1 are set lower than total aflatoxin levels which highlights the need to test these two measures independently.

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