Latest Articles

Researchers Discover a Promising Drug Target for Bowel Cancer
Article

The identification of this target is particularly exciting as it is unique to tumour cells, meaning that it is less toxic compared to existing therapies.

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Cryopreservation Freezing Methods and Equipment
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This article will describe the workflow, methods and equipment used for freezing, storage and thawing samples.

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Studying the Role of Astrocytes and Microglia in Neurodegenerative Disease: in vivo animal models or in vitro cell culture?
Article

New in vitro cell culture methods, such as three-dimensional co-cultures of primary human cells that more accurately mimic the in vivo multicellular environment can, therefore, complement or even replace in vivo studies using animal models.

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Organoids: The mini-organs advancing the study of human development and disease
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A "hot topic" in the last few years, organoids are becoming very attractive tools to study human development and disease.

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Umbilical Cord-Derived Stem Cells Could Help Those with Heart Failure
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Umbilical cord-derived stem cells could be the answer for patients with heart failure. A study published yesterday, indicates that cardiac muscle function and quality-of-life could be enhanced after treatment with this specific type of stem cell.

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Encouraging Step Towards a Potential Therapeutic Strategy for Asthma
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Researchers have discovered a compound with the ability to induce long-lasting bronchorelaxation and prevent hyperreactivity in murine models of asthma.

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Overcoming Challenges in Biopharma Quantitation with LC-MS
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In order to develop an effective LC-MS method to quantify biotherapeutics, technologies should be paired with reliable protein digestion and purification strategies, supported by liquid chromatography instruments that can deliver optimum levels of resolution, sensitivity and throughput.

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Could a Lipid be the Key to Treating Chronic Inflammatory Diseases?
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The lipid, 10-nitro-oleic-acid, an endogenous nitro-fatty acid (NFA) modulator, is being explored as a treatment for chronic inflammatory diseases. Prof. Valerie O'Donnell's group was one of the few that originally identified the lipid’s ability to reduce inflammation.

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LipidFinder: An Open-Source Python Workflow for Novel Lipid Discovery
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Researchers at the University of Cardiff, UK have developed a Python based computational workflow that is tailored to the analysis of large volumes of data, with the ability to identify novel lipids.

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Transitioning to Cloud-based Solutions Within the Clinical Research Industry
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Many in the clinical research industry are transitioning to cloud-based solutions for improved medical research and drug development efficiency. Big data analytics and distributed computing are two cloud-based techniques which can centralize computational and research tools.

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