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Drug Discovery

Drug Discovery

Featured Articles

Multichannel pipette dispensing samples into a 96-well plate during high-throughput screening.

How High-Throughput Screening Is Transforming Modern Drug Discovery

This article explores how advances in automation, 3D cell models and AI are transforming high-throughput screening, driving faster and more predictive drug discovery.

Digital interface with icons for policies, regulations and law highlighting data compliance concepts.

Data Compliance: Can AI Help Users Navigate New Technologies and Regulations?

AI tools are reshaping how labs handle compliance, from automating audit trails to improving data reuse and accuracy. In this article, we examine how the rise of AI is transforming compliance and how users can stay informed.

3D illustration of an adeno-associated virus (AAV), commonly used in gene therapy research.

Techniques and Advancements in Recombinant Adeno-Associated Virus Purification for Gene Therapies

This article examines key innovations driving scalable, high-yield purification of recombinant AAVs and how they’re helping overcome manufacturing bottlenecks in gene therapy.

Latest Articles

Black History Month: Pride and Power in Scientific Discovery

In celebration and support of UK Black History Month and this year’s theme, “Standing Firm in Power and Pride,” this article explores diversity in science and how it shapes who leads research and who benefits from it.

Humans standing in the shape of DNA.

Rethinking Sex, Gender and Sexuality in Genomic Research

Experts at ASHG 2025 will tackle clinical and genetic research challenges on sex, gender and sexuality, exploring ethics, advocacy and inclusion.

Digital model of a human liver glowing on a dark blue background.

The Future of Liver Health: Can Human Models and Machine Learning Reduce Disease Rates?

Explore how new innovations are bringing fresh hope for the future of liver health in the form of predictive, human-relevant research tools that can be used to understand disease and accelerate the development of novel therapies.

The word schizophrenia highlighted in pink in a dictionary definition.

Synaptic Regeneration: A New Frontier in Schizophrenia Treatment

Schizophrenia care is shifting. In this article, Dr. Stella Sarraf, founder and CEO of Spinogenix, and Dr. David Walling, co-founder and chief clinical officer at Cenexel, discuss a new frontier: synaptic regeneration.

Close-up of pipette tips dispensing green liquid into a microplate for high-throughput screening.

High-Throughput Screening: Principles, Applications and Advancements

Understand how high-throughput screening works and why it's crucial for faster, more efficient small molecule and biologics discovery.

Academic textbooks laid open on a table reflecting academic publishing.

Publish Less, Publish Better: Scientists Call for Predatory Publishing Practices To Stop

In a recent editorial, Professor Timmis and colleagues issued a call to action: restore the science ethos, re-establish quality as the cornerstone of research publishing and work collectively to dismantle the systems that incentivize poor practice.

3D rendering of nanoparticles designed for targeted drug delivery in a biological environment.

Innovative Drug Delivery Systems for Precision Medicine

This article explores innovative drug delivery strategies, including DNA barcoding, shape-engineered nanoparticles and biomimetic nanovesicles, highlighting their role in improving precision medicine and therapeutic safety.

Close-up illustration of neural stem cells potentially used for Alzheimer’s disease research.

Stem Cell Advances Reshape Alzheimer’s Research and Treatment

This article explores how stem cell therapies and organoid models are advancing Alzheimer’s research. It highlights progress in microglial replacement, patient-derived brain models and the use of AI to accelerate discovery.

Starry night sky with a lone explorer on a peak, representing imagination and night science.

The Night Science Institute Is Changing How Science Teaches Creativity

In this interview with Professors Itai Yanai and Martin Lercher, explore how night science brings creativity, ideation and collaboration back into the heart of modern science.

3D rendering of two protein molecules with three small drug molecules floating around and one fitting into a pocket within the proteins.

High-Throughput Effector Protein Remodeling for Molecular Glue Drug Discovery

Molecular glues hold strong therapeutic promise for approaches such as targeted protein degradation (TPD) and beyond, yet systematic identification remains challenging. But GlueSEEKER could help to overcome this problem.

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