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Latest Articles

How Drug–Diagnostic Co-development is Shaping Discovery Research and Pharmacotherapy
Article

This article reviews the importance and requirements for developing successful drug–diagnostic co-development models. It also highlights current challenges and ongoing efforts to address these issues, bringing us closer towards a more promising future for pharmacotherapy and patient care.

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Post-translational Modifications in Biopharmaceuticals
Article

This article provides insights on the impact of post-translational modifications of biopharmaceutical products on drug development and biotherapeutic formulation.

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Addressing the Underrepresentation of Women in Science
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We recently spoke with Jessica Wade, PhD, a physicist at Imperial College London to learn more about her extraordinary efforts to raise the profile of female scientists and other underrepresented groups in science.

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Incentivizing Drug Development for Rare Diseases
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On Rare Disease Day 2019, we discuss how regulatory incentives are necessary for encouraging rare disease drug development, and share the testimonial videos from this year's international campaign.

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The Hunt for Therapeutic Antibodies
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Given the clinical success that antibodies (formerly known as “magic bullets”) have facilitated, the drug discovery field continues to search for new therapeutic candidates. This article highlights several techniques used in the process, and touches on current trends driving the field.

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Pharmaceutical R&D Powered by MALDI Mass Spectrometry Imaging
Article

In order to design and develop new pharmaceutical compounds, the distribution of drugs and their metabolites in tissues must be determined. The emergence of advanced mass spectrometry techniques, such as MALDI imaging, have been pivotal in advancing the field.

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Cell Metabolism and Cancer
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It’s almost 100 years since Otto Warburg’s observation that cancer cells metabolize glucose in a manner that is distinct from that of cells in normal tissues. Yet, we still don’t fully understand why. In the years since, significant effort and resource has focused on understanding cancer-specific metabolic changes. Today, attention is also turning to the metabolic interaction between a tumor and its host.

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Pluripotent Stem Cells in Drug Discovery: Can We Stem the Tide of Unsuccessful Drugs?
Article

Stem cells were first discovered in human cord blood in 1978. Why would we think they can be of more help now? This article delves into reasons behind the sudden interest in stem cells, and highlights how they can be used to advance drug discovery.

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Addressing Controversy in ADHD: An Interview with Russell A. Barkley, PhD
Article

We interviewed Russell A. Barkley, PhD, an internationally recognized expert on attention-deficit hyperactivity disorder (ADHD), to gain an insight into the disorder, its portrayal in the media and the future of ADHD research.

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Recent Advances in Liquid Biopsy for Cancer
Article

Liquid biopsies for cancer search for evidence of disease biomarkers, the most common of which include circulating tumor cells, cell-free nucleic acids, exosomes, proteins and phosphoproteins. Read on for insights on advances in the field that could revolutionize clinical oncology practice.

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