Latest Articles
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Risk Assessment and Expert Review of N-Nitrosamine Contaminants
In this article, David Elder discusses the identification of N-nitrosamine impurities in valsartan drug substances products in mid-2018 and highlights the regulatory response, sources of contamination and analytical methods used for identifying nitrosamines.
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European Proteomics Infrastructure Consortium – Providing Access
The European Proteomics Infrastructure Consortium providing Access, or EPIC-XS, started in January 2019. It brings together a consortium of world-leading, highly innovative European proteomics facilities with the shared goal of supporting excellent life sciences research in Europe. In this article, Martina O'Flaherty provides an overview of some of the successes of the consortium so far.
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COVID-19 Vaccine Safety in Pregnancy
What are the benefits and risks for pregnant persons when it comes to COVID-19 and the vaccines, and does the benefit of the vaccine outweigh the risk of infection? Amber Schmidtke explores the scientific data available.
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Examining Risk–Benefit Profiles for Vaccines
In this article, David Elder, explores the risk–benefit profiles for various COVID-19 vaccines and discusses the steps taken by regulatory agencies in response to the occurrence of rare blood clotting events associated with the Oxford–AstraZeneca vaccine.
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Why mRNA Vaccines Could Be a Game Changer
In this article, Amber Schmidtke explores why mRNA vaccines might chart our path to a safer, healthier future.
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Gut Microbiome Changes Identified After Spinal Cord Injury
A pilot study led by Professor Phillip Popovich has placed focus on how traumatic SCI might impact the gut microbiome – the population of microbes inhabiting the digestive tract. We spoke to study author Ahmed Zayed to find out more.
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Changing Up the Route of Vaccine Administration
In this article, we discuss the various routes of vaccine administration and highlight key innovations in this space.
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COVID-19 Vaccines and Therapeutic Development
Scientists are concerned about the emergence of SARS-CoV-2 variants and whether existing vaccines will remain effective against them. Hence, the development of robust therapeutic systems, such as repurposing drugs, could aid in managing the pandemic more efficiently. This article discusses the different vaccines and potential treatments developed thus far.
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High-Throughput Screening: Using a More Intelligent Approach for Hit Discovery
While industrial laboratories can screen vast numbers of potential drug compounds, many academic researchers are adopting more focused strategies.
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COVID-19 Vaccine Storage and Stability
COVID-19 vaccines are here, they are headed out globally and the world is faced with a giant logistical task: keeping these vaccines in their desired storage conditions to ensure stability and efficacy of every dose that goes into an arm. What are the storage requirements of vaccines and why does it matter?
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