We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Latest Articles

UK Lung Cancer Diagnostic Services: Time to Step Up
Article

The UK’s national health system needs to take a hard look at their priorities and procedures to ensure that rapid advances in molecular diagnostics in lung cancer are translated into a practical service for all patients, according to a report launched at the British Thoracic Oncology Group Annual Conference.

READ MORE

Overcoming the Identification Bottleneck in Untargeted Metabolomics: Combining Technological and Software Innovations
Article

Untargeted metabolomics approaches are allowing previously unreported insights into the pathogenesis of disease. However, identifying the large numbers of unknown and structurally diverse metabolites typically present in biological samples has proven to be a major bottleneck. Fortunately, recent advances in technology and software are helping to overcome this challenge.

READ MORE

A Renaissance for Microflow Liquid Chromatography Mass Spectrometry?
Article

First developed in the 1970s, recent developments are making microflow liquid chromatography techniques more robust – enticing researchers to revisit the opportunities it offers for more sensitive, high-throughput analyses requiring smaller sample volumes than standard flow techniques.

READ MORE

Big Data Analysis Approaches for Drug Discovery
Article

Big data has long been a buzzword in drug discovery, but as analysis methods become more sophisticated, its potential is beginning to be realized. We look at some of the latest advances in big data analysis for drug discovery.

READ MORE

Overcoming Challenges in Biopharma: Transformational Innovation is Key
Article

Looking at the industry growth and the complexities of biopharma development, it is no wonder that transformational developments are required to better equip laboratories and operations in biopharma.

READ MORE

Quantifying Minimal Residual Disease in Chronic Myeloid Leukemia
Article

Thanks to advances in therapeutics, chronic myeloid leukemia has been transformed from a deadly cancer into a manageable, chronic condition. However, patients have to stay on these drugs their whole lives, as there isn't a diagnostic test sensitive enough to detect traces of the disease that threaten a relapse. This article delves into the unmet need for such a test, and explains why droplet digital PCR (ddPCR) is a strong candidate that may fill this gap.

READ MORE

The Biochemistry and Pharmacologic Properties of Cannabis-derived Terpenoids
Article

Terpenoids are responsible for the unique aroma of cannabis. These compounds are lipophilic, can permeate lipid membranes, and several are capable of crossing the blood-brain barrier after inhalation. We recently spoke to Ethan Russo, MD, to learn more about the biochemistry and potential pharmacologic properties of cannabis-derived terpenoids.

READ MORE

Neutrons – A New Weapon Against Cancer
Article

The development of cancer is a complex process, which can result from minor mistakes in an otherwise well-functioning network of cellular processes. As such, it is essential that scientists have a clear picture of biochemical processes at an atomic level in order to gain an in-depth understanding of how various cancers occur and develop. One technique starting to gain recognition as a powerful tool is neutron crystallography.

READ MORE

Cell Signaling in Cancer
Article

This article discusses the relationship between cell signaling and cancer, highlights key signaling pathways involved in cancer, and explores how critical mediators of aberrant signaling can be turned into therapeutic targets for cancer.

READ MORE

Discovering Druggable Targets
Article

We recently spoke to Dr Kilian V. M. Huber from the Structural Genomics Consortium & Target Discovery Institute, University of Oxford to find out – ‘What makes a good target?’.

READ MORE