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Latest Articles

Could a New Project Expose Predatory Conferences?
Article

The rise of predatory conferences jeopardises the future of legitimate research events. But could conference IDs be the solution?

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Pressure to Fight Vaccine Hesitancy As Measles Cases Soar
Article

The UK has lost its measles-elimination status. New York have removed nonmedical exemptions from school vaccination requirements. Italy have made a number of vaccines mandatory. Here, we explore how global health authorities are tackling the issue of vaccine hesitancy as the number of measles cases continues to rise.

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Angiogenesis in Cancer
Article

In this article we take a look at the relationship between angiogenesis and cancer, highlight the role of p38α in the regulation of angiogenesis, explore the existence of non-angiogenic tumors, and discuss the ways to therapeutically target angiogenesis.

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Therapeutic Gene Editing for Sickle Cell Disease
Article

Sickle cell disease is the most common inherited blood disorder in the US, affecting > 70,000 Americans. Christopher Vakulskas, Senior Staff Scientist, Integrated DNA Technologies discusses efforts to develop a sickle cell disease therapy using CRISPR gene editing.

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Why Science Can’t Afford Mistakes When It Comes to Cell Line Authenticity
Article

Having strains and cell lines that have been checked and confirmed to be what it says on the tube is invaluable to scientific validity and integrity, saving untold time and money. We spoke to Mindy Goldsborough, Ph.D., Chief Science and Technology Officer, VP and General Manager, ATCC Cell Systems about the importance and challenges of maintaining authenticated cell lines for scientific research.

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"MOSAIC" HIV Vaccine to be Tested in Thousands Globally
Article

A clinical trial testing a "mosaic" HIV vaccine is due to commence in September. The trial is pertinent considering a recent UNAIDS report expressed concerns that the pace of progress in reducing new HIV infections has slowed. This article discusses the plans for the trial and the current status of vaccine research in the field.

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In the Search for New Lead Compounds – The Latest Medicinal Chemistry Impact Stories
Article

Here we will take a deep dive into the world of modern medicinal chemistry and learn how scientists are continuously innovating to find drug candidates and get the best ones to market and into your hands.

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How Far Can Organs-on-Chips Go On Their Own?
Article

Great hope has been placed on organ-on-chip models to provide a complex and predictive in vitro models that can recapitulate the human drug response. How far can they go? This article delves into whether organ-on-chips can live up to expectations, and in particular, whether they can do it alone.

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More Diverse Genomic Databases Can Tackle Healthcare Inequalities
Article

Genetic analysis is now a common part of diagnosis or treatment for many conditions, and targeted treatments based on specific genetic variants have made personalized medicine a reality. Research has shown that most of the genetic knowledge we have is based on the genomes of a select group of individuals. This article explores how using more diverse genomic databases can help tackle healthcare inequalities.

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Drug Delivery
Article

By finding the best-suited delivery mechanism for a specific drug molecule it is possible to “optimize” the performance of that drug inside the body. Here we take a look at the different administration methods, discover what is meant by a "drug delivery system", and highlight key drug delivery “vehicles”.

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