The UK has lost its measles-elimination status. New York have removed nonmedical exemptions from school vaccination requirements. Italy have made a number of vaccines mandatory. Here, we explore how global health authorities are tackling the issue of vaccine hesitancy as the number of measles cases continues to rise.READ MORE
Sickle cell disease is the most common inherited blood disorder in the US, affecting > 70,000 Americans. Christopher Vakulskas, Senior Staff Scientist, Integrated DNA Technologies discusses efforts to develop a sickle cell disease therapy using CRISPR gene editing.READ MORE
Having strains and cell lines that have been checked and confirmed to be what it says on the tube is invaluable to scientific validity and integrity, saving untold time and money. We spoke to Mindy Goldsborough, Ph.D., Chief Science and Technology Officer, VP and General Manager, ATCC Cell Systems about the importance and challenges of maintaining authenticated cell lines for scientific research.READ MORE
A clinical trial testing a "mosaic" HIV vaccine is due to commence in September. The trial is pertinent considering a recent UNAIDS report expressed concerns that the pace of progress in reducing new HIV infections has slowed. This article discusses the plans for the trial and the current status of vaccine research in the field.READ MORE
Here we will take a deep dive into the world of modern medicinal chemistry and learn how scientists are continuously innovating to find drug candidates and get the best ones to market and into your hands.
Great hope has been placed on organ-on-chip models to provide a complex and predictive in vitro models that can recapitulate the human drug response. How far can they go? This article delves into whether organ-on-chips can live up to expectations, and in particular, whether they can do it alone.READ MORE
Genetic analysis is now a common part of diagnosis or treatment for many conditions, and targeted treatments based on specific genetic variants have made personalized medicine a reality. Research has shown that most of the genetic knowledge we have is based on the genomes of a select group of individuals. This article explores how using more diverse genomic databases can help tackle healthcare inequalities.READ MORE
By finding the best-suited delivery mechanism for a specific drug molecule it is possible to “optimize” the performance of that drug inside the body. Here we take a look at the different administration methods, discover what is meant by a "drug delivery system", and highlight key drug delivery “vehicles”.READ MORE