We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Latest Articles

Native Mass Spectrometry: A Glimpse Into the Machinations of Biology
Article

The question perhaps is not when native mass spectrometry can be used; but rather, when can’t it be used? Today, the applications are broad-reaching and diverse. This article shares insights from innovators in the field who have helped establish this incredibly useful analytical technique.

READ MORE

MeTooSTEM: A Mission to End Sexual Harassment in STEM
Article

In the wake of the "Me Too" (or #MeToo) movement, a spotlight has been cast on an additional obstacle that deters many individuals, particularly women, from working in STEM – the astonishingly high incidence of sexual harassment. In this article, we look at the extent of the issue and speak with some of the women that are working tirelessly to combat sexual harassment in STEM through a variety of organizations.

READ MORE

Next-Generation Sequencing (NGS): Stimulating the Next Generation of Cancer Diagnostics and Treatment
Article

The "molecular age" of cancer research is here, thanks to advances in next generation sequencing (NGS) which have catalyzed progress in countless areas of cancer research. Find out about the latest studies where NGS is improving our ability to detect cancer, match the best drugs to patients, and monitor treatment success.

READ MORE

Antibodies in Research: The Good, the Bad, and the Validation Epidemic
Article

The specificity of antibody binding is incredibly important for many research disciplines, yet sourcing the best antibody for your research can be a challenge. This is partly because not all suppliers validate their antibodies sufficiently. How much of a problem is this?

READ MORE

Why Does Ketamine Fight Depression? Finding Answers at BNA 2019
Article

A significant minority of major depressive disorder patients don’t respond to currently available antidepressant medication. A newly approved treatment, based on the "club drug" ketamine, could change that. In a session at the British Neuroscience Association’s Festival of Neuroscience 2019, the potential mechanisms of ketamine’s antidepressant action were put under examination.

READ MORE

The Evolving Field of Cancer Biomarkers
Article

Given the complexity of cancer, it’s arguably unlikely that single molecules will work as clinically meaningful biomarkers for cancer. Today, biomarker discovery involves detecting patterns – characteristics or phenotypes that can be measured and monitored throughout a patient’s journey. Here, we look at two approaches being explored in this evolving field.

READ MORE

Sensitivity vs Specificity
Article

When developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.

READ MORE

A Further Dimension to Drug Discovery: Combining 3D Culture With iPSCs
Article

Running in parallel with advances in 3D cell culture is the growing use of human cells derived from induced pluripotent stem cells. Researchers are interested in testing drugs in the most physiologically relevant models possible, so it was only a matter of time before these two approaches converged – providing optimized systems for disease modeling and drug toxicity testing.

READ MORE

Preclinical Modeling of Tumor Metastasis and Resistance: Current Challenges and New Approaches
Article

To improve cancer survival rates, pharma and biotech researchers must develop safe and effective therapies to treat not only primary tumors, but also metastatic growths and tumors that have acquired resistance.

READ MORE

The Power of Proteogenomics in Precision Medicine
Article

Part of the "systems biology" trend, proteogenomics is expanding at an accelerating rate. In this article, we look at the approaches adopted in proteogenomics and explore how proteogenomics is changing the dynamics of precision medicine in oncology.

READ MORE