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Adamantyl-Containing Ligands for Challenging Cross-Coupling Reactions

While adamantyl-containing phosphine ligands are well established for drug development purposes and in academic settings, the number of reported large-scale applications are easily counted on the fingers of one hand. However, as the reaction scope for adamantyl-phosphine based catalysts continue to be expanded and their favorable properties are better understood, it is likely that their role in process development R&D and production will increase.

Download this eBook to discover:

  • Factors influencing a ligand or catalyst’s suitability for production
  • Prominent classes of adamantyl-based phosphine ligands
  • Industrial applications of Adamantyl-containing phosphine ligands