Polymorphism & Crystallisation, New Orleans, LA, USA
Event Mar 22
The reproducible production of organic crystals in the correct form (habit, solvate, polymorph) and particle size is a subject which causes much heart-ache to chemists, engineers, pharmacists and formulators. Although production of new polymorphs and solvates can be a source of profit for companies through extention of the patent lifetime, the inability to manufacture a consistent crystalline form often leads to costly project delays, particularly in chemical development.
This symposium will focus on these issues from the viewpoint of the process chemist and chemical engineer; ie on chemical development issues which impact the ability to routinely manufacture the chosen crystalline form, whether this be the most stable or a metastable crystal. Case studies from different companies will show how different organisations identify and solve these extremely difficult issues in different ways, depending on how far the project is along the development time line. Experts in the field will also give lectures on problem solving and troubleshooting, as well as giving insight into new techniques, (supercritical fluids, polymorph prediction etc.) which should be of value in the future